Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Strength, Microstructural, and Environmental Performance of Phosphogypsum-GGBS-Carbide Slag Ternary Blended Cement. [PDF]
Tan Y, Essama JRA, Wang C, Wu J, Ming H.
europepmc +1 more source
Enviromental Performance and Regional Innovation Spillovers [PDF]
The achievement of positive environmental performance at national level could strongly depend on differences in local capabilities of both institutions and the private business sector.
Anna Montini +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Evaluating Environmental Performance of PLA-Cellulose-Based Biocomposites: A Comprehensive Study on Biodegradability, Compostability, and Ecotoxicity. [PDF]
Costa VLD +12 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
From ethics to ecology: How ethical leadership drives environmental performance through green organizational identity and culture. [PDF]
Rihal J +3 more
europepmc +1 more source
Economic and Environmental Performance of an Integrated CO2 Refinery. [PDF]
Ioannou I +3 more
europepmc +1 more source
An assessment of the construct validity of environmental strategy measures [PDF]
The natural resource-based view of the company is emerging as a dominant paradigm for understanding the intersection of strategic management and the natural environment.
Berrone, Pascual +2 more
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source

