Results 81 to 90 of about 3,729,294 (289)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

New Perspectives for the Resistance Training of Runners: Flywheel Approach

open access: yesInternational Journal of Strength and Conditioning
Strengthening muscle is a critical aspect of injury resistance and training for performance gain, and as such, a wide variety of resistance training methods are available to the coach.
Chloe Ryan   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Integrative Review of Strength Milestoning in Mid-Stage Achilles Tendon Rehab

open access: yesBiomechanics
Current rehabilitation protocols for transitioning patients to late-stage recovery, evaluating return-to-play (RTP) clearance, and assessing tendon characteristics exhibit significant heterogeneity.
Chris Toland   +4 more
doaj   +1 more source

How does environmental performance affect financial performance? Evidence from Japanese manufacturing firms [PDF]

open access: yes
This paper examines the effects of environmental performance on financial performance using the data of Japanese manufacturing firms from 2004 to 2008. As the environmental performance, our study considers the two different environmental issues of waste ...
Iwata, Hiroki, Okada, Keisuke
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Effects of Environmental Policy on the Performance of Environmental RIVs [PDF]

open access: yes
Much of the potential impact of environmental policy is though to come from the incentives it gives firms to develop and introduce new environmental products and processes.
Alistair Ulph   +2 more
core  

The key role of institution pressure on green supply chain practice and the firm's performance [PDF]

open access: yes, 2019
Purpose: This study was conducted to investigate the influence of isomorphism institutional theory on green supply chain management (GSCM) and firm performance by using the structural equation model (SEM) to explain the driving factors of reducing the ...
Saenchaiyathon, Krittapha   +1 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effects of Ownership and Financial Status on Corporate Environmental Performance [PDF]

open access: yes
This paper analyzes the effects of ownership structure on corporate environmental performance and examines the link between financial performance to environmental performance in a transition economy. In particular, it analyzes these ownership effects and
Dietrich Earnhart, Lubomir Lizal
core   +3 more sources

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