Results 171 to 180 of about 1,213,044 (313)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Consumer Society, Environmental Performance Index And Evaluation of Environmental Performance For Turkey According To Environmental Performance Index

open access: yes, 2012
Environmental Performance Index (EPI-Environmental Performance Index) is a major study which evaluates environmental health and ecosystem vitality of countries, two years apart. This study, prepared by Yale University and based on 16 performance indicators in 2006, 25 in 2008 and 2010, and finally 22 in 2012, evaluating the environmental performance ...
openaire   +1 more source

Environmental Regulations and Environmental Performance: A Review

open access: yesScholars Journal of Arts, Humanities and Social Sciences
The rapid growth following the Industrial Revolution has led to various environmental issues. Integrating environmental management into broader strategic frameworks is essential for fostering a sustainable competitive advantage. Many countries have taken proactive steps to safeguard public environmental rights and promote sustainable economic ...
openaire   +1 more source

The US Agriculture Greenhouse Emissions and Environmental Performance

open access: yes
Replaced with revised version of paper 09/23/11.Productivity, Technical Efficiency, environmental performance, Production Economics, Productivity Analysis, Resource /Energy Economics and Policy,
Kabata, Tshepelayi
core   +1 more source

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