Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Integrating marker-assisted identification and multi-environment trait stability models to select superior rice restorer lines for hybrid breeding. [PDF]
Ragi S +15 more
europepmc +1 more source
CISEF: a composite index of social, environmental and financial performance
Summarization: We propose a holistic evaluation framework that banks could adopt when screening corporate entities. The framework is based on the development of a composite indicator of social, environmental and financial performance. This integrated view of evaluation is conceptually aligned with ISO standards and empirical proposals of academics and ...
Γαγανης Χρυσοβαλαντης(http://users.isc.tuc.gr/~cgaganis) +6 more
openaire +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Disaggregating innovation for sustainable development in ASEAN: Panel evidence on the moderating role of government effectiveness. [PDF]
Irikefe PO +5 more
europepmc +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
A sustainability-oriented supply chain supplier selection framework using resilience and HSE performance metrics in the automotive industry. [PDF]
Maddah S +5 more
europepmc +1 more source
Material environmental performance index method in green design
openaire +1 more source
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah +7 more
wiley +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source

