Results 101 to 110 of about 1,131,915 (294)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Environmental Psychology

, 2012
This book aims to give an introduction in environmental psychology. We defi ne environmental psychology as the discipline that studies the interplay between individuals and their built and natural environment. This means that environmental psychology examines the infl uence of the environment on human experiences, behaviour and well - being, as well as
Steg, L., van den Berg, A.E., de Groot, J.I.M.   +2 more
openaire   +4 more sources

Editorial: Current trends in environmental psychology, volume I. [PDF]

Front Psychol, 2023
De Gregorio E, Caffaro F, Pirchio S, Tiberio L, Carrus G.   +4 more
europepmc   +1 more source

Transforming environmental psychology

Journal of Environmental Psychology, 2009
Although it is recognised that the individual and the external world are linked in complex and mutual ways and can only be treated together as one phenomenon there is little evidence that transactionalist approaches, despite potentially providing a truly distinctive approach for environmental psychology, have been fully understood or operationalised ...
Uzzell, D, Rathzel, N
openaire   +4 more sources

The Psychosocial Work Environment, Employee Mental Health and Organizational Interventions: Improving Research and Practice by Taking a Multilevel Approach [PDF]

, 2014
Although there have been several calls for incorporating multiple levels of analysis in employee health and wellbeing research, studies examining the interplay between individual, workgroup, organizational and broader societal factors in relation to ...
Arnetz, Bacharach, Bamberger, Biron, Biron, Biron, Biron, Bliese, Bliese, Bonde, Bourbonnais, Bourbonnais, Briner, Burke, Capelli, Chan, Clegg, Clegg, Cole, Cooper, Cox, Dawkins, De Silva, Demerouti, Dextras-Gauthier, Diez-Roux, Dollard, Dollard, Dollard, Dollard, Dollard, Dollard, Ferrie, Giga, Goldenhar, Graveling, Greenberg, Hackman, Hall, Hargrove, Hofmann, Hurrell, James, James, Jauvin, Johns, Karanika-Murray, Karasek, Katz-Navon, Kelloway, Klein, Klein, Kolstad, Kompier, Kuenzi, Kulik, Lamontagne, Lamontagne, Li, Maloney, Marchand, Martin, Melchior, Mellor, Mischel, Mitchell, Murphy, Newman, Nicholson, Nielsen, Nielsen, Oakley, Ostroff, Patterson, Pawson, Peterson, Pignata, Probst, Quick, Randall, Reichers, Rousseau, Rousseau, Rousseau, Saksvik, Schein, Schminke, Schneider, Schneider, Schneider, Schyns, Seibert, Semmer, Siegrist, Sorensen, Spell, Stansfeld, Taris, Ukoumunne, Van Yperen, Waldenstrom, Walsh, Walumbwa, Weick, Ylipaavalniemi, Zohar   +105 more
core   +1 more source

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

Advanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo, Fangzhi Lou, Peiran Yang, Yu Zhang, Li Yan, Yunmei Dong, Bing Yang, Haiyang Wang, Yiyun Liu, Juncai Pu, Richard D. Cannon, Peng Xie, Ping Ji, Xin Jin   +13 more
wiley   +1 more source

Socio-psychological aspects of grassroots participation in the Transition Movement: An Italian case study [PDF]

, 2016
In this article, we present a case study investigating the socio-psychological aspects of grassroots participation in a Transition Town Movement (TTM) community initiative.
Armenti, Alessandra, Biddau, Fulvio, Cottone, PAOLO FRANCESCO   +2 more
core   +2 more sources

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Climate Change and Individual Decision Making: An Examination of Knowledge, Risk Perception, Self-interest and Their Interplay [PDF]

In this essay, three separate yet interconnected components of pro-environmental decision making are considered: (a) knowledge, in the form of basic scientific understanding and procedural knowledge, (b) risk perception, as it relates to an individual’s ...
Francesca Pongiglione
core  

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source