Results 91 to 100 of about 2,358,637 (310)

Post–Synthetic Modification of MOF–808 for Mixed Matrix Membranes with High and Stable Ion Separation Capacity

Molecules
The global clean water crisis is a pressing sustainable development challenge that demands urgent solutions. Membrane separation technology has emerged as a leading approach for seawater desalination, offering great potential to address freshwater ...
Bahar Karadeniz, Han-Liang Fang, Yi-Ying He, Qi-Lin Ye, Jun-Yu Chen, Jian Lü   +5 more
doaj   +1 more source

Development of two enzyme-linked immunosorbent assay formats for thifluzamide residues’ analysis based on distinct polyclonal antibodies

Food and Agricultural Immunology, 2018
Haptens 2-Methyl-4-(trifluoromethyl)thiazole-5-carboxylic acid and 2,6-Dibromo-4-(trifluoromethoxy)aniline, the two moieties of thifluzamide, were conjugated with carrier proteins for the synthesis of artificial antigens.
Xiaoxiao Li, Yun Zhao, Shumao Ding, Huihui You, Weiyong Feng, Xu Yang, Junlin Yuan   +6 more
doaj   +1 more source

Variation in Environmental Regulations in California and Effects on Dairy Location [PDF]

In recent decades, urban encroachment and increasing environmental regulation have impacted California’s dairy industry. A complicated set of environmental legislation affects dairies in the state, and can differ depending on location, creating the ...
Hogle, Regina, Sneeringer, Stacy E.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Harnessing phage consortia to mitigate the soil antibiotic resistome by targeting keystone taxa Streptomyces

Microbiome
Background Antimicrobial resistance poses a substantial and growing threat to global health. While antibiotic resistance genes (ARGs) are tracked most closely in clinical settings, their spread remains poorly understood in non-clinical environments ...
Hanpeng Liao, Chang Wen, Dan Huang, Chen Liu, Tian Gao, Qiyao Du, Qiu-e Yang, Ling Jin, Feng Ju, Mengting Maggie Yuan, Xiang Tang, Pingfeng Yu, Shungui Zhou, Pedro J. Alvarez, Ville-Petri Friman   +14 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Three New Empirical Tests of the Pollution Haven Hypothesis When Environmental Regulation is Endogenous [PDF]

The validity of existing empirical tests of the Pollution Haven Hypothesis (PHH) is constantly under scrutiny due to two shortcomings. First, the issues of unobserved heterogeneity and measurement error in environmental regulation are typically ignored ...
Daniel L. Millimet, Jayjit Roy
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

CRISPR/Cas9-Mediated Knockout of BnaFAH Enhanced Brassica napus Resistance to Plutella xylostella Under a 2-Day Short-Day Photoperiod

Horticulturae
The diamondback moth (Plutella xylostella) severely threatens global oilseed rape (Brassica napus L.) production. This study demonstrates that CRISPR/Cas9-mediated knockout of two homologous BnaFAH, involved in tyrosine degradation, confers enhanced ...
Tiantian Zhi, Zhou Zhou, Chen Shi, Meiqiong Xie, Gang Chen, Cui Lu   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source