Results 121 to 130 of about 2,358,637 (310)
Formal and informal regulation of industrial pollution : comparative evidence from Indonesia and the United States [PDF]
The authors start from the premise that governments act as agents of the public in regulating pollution, using the instruments at their disposal. But when formal regulatory mechanisms are absent or ineffective, communities will seek other means of ...
Hettige, Hemamala +3 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
EMBO ReportsDecitabine (DAC), a well-recognized DNA hypomethylating agent, has been applied to treat acute myeloid leukemia. However, clinic investigations revealed that DNA methylation reduction does not correlate with a clinical response, and relapse is prevalent.
Pinqi Zhang +8 more
doaj +1 more source
When and why does it pay to be green? [PDF]
Environmental policy; innovation; Porter hypothesis; environmental regulation; pollution; capital market; green products.
Paul Lanoie, Stefan Ambec
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Towards an evolutionary environmental regulation of capitalism : sustainable development 20 years after [PDF]
The paper argues that by combining ecological economics, IPE and regulation approaches more closely, one may provide an account of the apparent contradiction between the utopian aspect of sustainable development and the ability of capitalism to ...
Jean Christophe Graz +2 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
SeparationsBiologically treated swine farm wastewater still contains high levels of refractory organics, humic substances and antibiotic residues, posing environmental risks and limiting opportunities for water reuse. Wastewater treatment by ozonation alone suffers
Hang Yu +6 more
doaj +1 more source
Environmental regulation and international trade patterns for agro-industrial under a South-North Perspective [PDF]
This paper aims at examining the relation between the international trade and the environment, particularly focused on sensitive agribusiness sectors. It consists on an empirical test to the conflicting positions supported by economists, some following ...
Barros, Geraldo Sant'Ana de Camargo +2 more
core +1 more source