Results 201 to 210 of about 778,376 (262)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The Public Interest in Fairness in Regulatory Processes

open access: yesMaine Policy Review, 1992
Elizabeth Swain
doaj  

A State Regulator's View of Environmental Regulation

open access: yesMaine Policy Review, 1992
Dean Marriott
doaj  
Some of the next articles are maybe not open access.

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The Regulation of Environmental Innovations

Journal of Environmental Economics and Management, 2002
In the paper an interesting model of the regulation of the environmental R\&D (research and development) projects with perfect and imperfect (asymmetric) information is presented. In the R\&D model the evaluation of projects is based (only) on the completion time.
Tsur, Yacov, Zemel, Amos
openaire   +2 more sources

Bargaining in Environmental Regulation and the Ideal Regulator

Journal of Environmental Economics and Management, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Amacher, Gregory S., Malik, Arun S.
openaire   +1 more source

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