Results 21 to 30 of about 7,449,547 (302)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Promotion of partial nitrification by hydroxylamine and differential responses of nitrifying microorganisms

Gongye shui chuli
Hydroxylamine can promote the establishment of partial nitrification. This study investigated its promoting effect from the dual perspectives of microbial activity and gene expression.
MIN Wenhui, SHI Liangliang, WEI Yan, PAN Zhonglin, LI Wen, MA Bin   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Strategy to mitigate substrate inhibition in wastewater treatment systems

Nature Communications
Global urbanization requires more stable and sustainable wastewater treatment to reduce the burden on the water environment. To address the problem of substrate inhibition of microorganisms during wastewater treatment, which leads to unstable wastewater ...
Beiying Li, Conghe Liu, Jingjing Bai, Yikun Huang, Run Su, Yan Wei, Bin Ma   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Environmental regulation in Indonesia [PDF]

, 1994
Since the early 1980s environmental regulation has received high priority in Indonesian policy making. Given Indonesia's dependence upon foreign donors for its economic program, external pressures inevitably played a significant role in stimulating this ...
ELSTON, KYLIE, Warren, C., WERREN, CAROL, Elston, K.   +3 more
core  

Image-Based Assessment of External Quality Traits in Chinese Bayberry (Myrica rubra) Using a Deep Learning Detection and Multi-Trait Scoring Framework

Foods
Chinese bayberry (Myrica rubra) is an extensively popular fruit with unique flavors and high nutritional values. A precise and efficient method for assessing external quality traits of Chinese bayberry is critical for machine automatic sorting to ensure ...
Mengting Wang, Lijia Lei, Hongdou Liang, Jiawei Jiang, Yalu Chen, Yunyan Hua, Tao Ma, Wona Ding, Xu Li   +8 more
doaj   +1 more source

Omics for understanding the tolerant mechanism of Trichoderma asperellum TJ01 to organophosphorus pesticide dichlorvos

BMC Genomics, 2018
Backgroud Though it is toxic to humans, dichlorvos is a widely used chemical pesticide and plays an important role in the control of plant pests. The application of a combination of the biocontrol agent Trichoderma with dichlorvos may reduce the need for
Qiong Wu, Mi Ni, Guisheng Wang, Qianqian Liu, Meixia Yu, Jun Tang   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source