Results 51 to 60 of about 7,449,547 (302)

The crystal structure of (E)-4-fluoro-N′-(1-(o-tolyl)ethylidene)benzohydrazide, C16H15FN2O

open access: yesZeitschrift für Kristallographie - New Crystal Structures
C16H15FN2O, monoclinic, Pc (no. 7), a = 12.3610(11) Å, b = 15.1269(17) Å, c = 8.1382(6) Å, β = 106.411(9)°, V = 1459.7(2) Å3, Z = 4, R gt(F) = 0.0565, wR ref(F 2) = 0.1315, T = 293 K.
Wang Chuyi   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The multichromosomal structure evolution of Dendrobium mitogenomes and new insights into interrelationships of recently radiated tribes in Epidendroideae (Orchidaceae)

open access: yesFrontiers in Plant Science
IntroductionEpidendroideae is the largest subfamily in Orchidaceae, comprising over 20,000 species in 16 tribes, which are renowned for their remarkable morphological diversity and beautiful flowers.
Mengting Wang   +10 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Functional Analysis of OsDRP2B in Rice Root Development

open access: yesPlants
Rice (Oryza sativa L.) root system plays a critical role in water and nutrient uptake, influencing overall plant growth and crop yield. In this study, we characterized the Osdrp2b mutant, which exhibits a short-root phenotype and was identified through ...
Lihuiying Jia   +12 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

NanoFe3O4 as Solid Electron Shuttles to Accelerate Acetotrophic Methanogenesis by Methanosarcina barkeri

open access: yesFrontiers in Microbiology, 2019
Magnetite nanoparticles (nanoFe3O4) have been reported to facilitate direct interspecies electron transfer (DIET) between syntrophic bacteria and methanogens thereby improving syntrophic methanogenesis.
Li Fu   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Environmental and wider economic implications of modifications to environmental tax reform [PDF]

open access: yes, 2002
The most common definition of Environmental Tax Reform (ETR) is the use of the revenue from environmental taxes to reduce distortionary labour taxes. However, the PETRAS project has shown that there are a number of social and political impediments to ...
Clinch, J. Peter, Dunne, Louise
core   +1 more source

Heterologous Watermelon HSP17.4 Expression Confers Improved Heat Tolerance to Arabidopsis thaliana

open access: yesCurrent Issues in Molecular Biology
Members of the heat shock protein 20 (HSP20) family of proteins play an important role in responding to various forms of stress. Here, the expression of ClaHSP17.4 was induced by heat stress in watermelon.
Yajie Hong   +8 more
doaj   +1 more source

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