Results 211 to 220 of about 1,549,340 (297)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Environmental law reports

Environment International, 1993
openaire   +1 more source

Establishing a community event-based surveillance system in Kadoma City, Zimbabwe: a mixed-methods study protocol. [PDF]

BMJ Public Health
Munemo C, Chirundu D, Juru T, Shambira G, Chadambuka A, Gombe N, Mandozana G, Tshimanga M.   +7 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Progress and challenges in development of minimum essential dataset for disease surveillance through a One Health lens: a scoping review. [PDF]

Infect Dis Poverty
Li T, Jia L, Qiang N, Zheng J, Ran J, Zhang X, Han L.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Environmental assessment report

Environmental assessment report of the new SOC materials and processing ...
openaire   +3 more sources

Environmental impact report [PDF]

Environmental Policy and Law, 1980
openaire   +1 more source

Systematic review on the laboratory methodology for conducting wastewater and environmental surveillance for <i>Salmonella</i>. [PDF]

Front Public Health
Sangal L, Sood V, Haar K, Silubonde TM, Jinnai Y, Rijal S.   +5 more
europepmc   +1 more source