Results 31 to 40 of about 188,724 (312)
International Journal of Agricultural Research, Innovation and Technology, 2021 The study was conducted to investigate the soil properties and pesticide intensity in rice, banana and brinjal growing agricultural land of Delduar and Sakhipur upazila of Tangail district during July 2019 to June 2020.
TN Shila +5 more
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Heliyon, 2021 Establishing model based balanced nutrient requirements for barley (Hordeum spp.) in the northern Ethiopia can solve the fertilizer recommendation problems and enhance crop yield.
Shimbahri Mesfin +4 more
doaj
Ecology and Society, 2014 Communities in the Great Bear Rainforest of British Columbia, Canada are highly dependent on Pacific salmon (Oncorhynchus spp.) and the watersheds that support them, yet current monitoring efforts are likely inadequate for detecting changes in stream ...
Cory R. Lagasse +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
On the Effect of the Absorption Coefficient in a Differential Game of Pollution Control
Mathematics, 2020 We consider various approaches for a characteristic function construction on the example of an n players differential game of pollution control with a prescribed duration.
Ekaterina Marova +3 more
doaj +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Investigation of soil properties and nutrients in agricultural practiced land in Tangail, Bangladesh
International Journal of Agricultural Research, Innovation and Technology, 2020 The study investigated on soil nutrients in agriculture practiced high, medium high, medium low and low land at Kalihati upazila of Tangail district during October 2017 to June 2018.
MS Islam +5 more
doaj +1 more source