Results 31 to 40 of about 203,753 (249)

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Small Sawmills Persevere While the Majors Close: Evaluating Resilience and Desirable Timber Allocation in British Columbia, Canada

open access: yesEcology and Society, 2013
We compared the resilience to economic shocks - such as the downturn of the U.S. housing market - of commodity sawmills, which tend to be large, and value-added specialty sawmills, which tend to be small or medium in size, that are located in one region ...
Evelyn W. Pinkerton, Jordan Benner
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Spatial distribution and diurnal variation of particulate matters and gaseous air pollutants of Dhaka city, Bangladesh

open access: yesDiscover Atmosphere
Air Pollution poses significant environmental and health challenges, particularly in South Asia, including Bangladesh, over the past two decades.
Mir Md. Mozammal Hoque   +8 more
doaj   +1 more source

Design considerations for community-based stream monitoring to detect changes in Pacific salmon habitats

open access: yesEcology and Society, 2014
Communities in the Great Bear Rainforest of British Columbia, Canada are highly dependent on Pacific salmon (Oncorhynchus spp.) and the watersheds that support them, yet current monitoring efforts are likely inadequate for detecting changes in stream ...
Cory R. Lagasse   +6 more
doaj   +1 more source

Coliform Bacteria Concentration in Okpon River, Obubra Local Government Area, Cross River State, Nigeria [PDF]

open access: yesRiscuri şi Catastrofe, 2019
Water pollution takes place in both rural and urban areas. Drinking water from sources like rivers, streams, lakes and ponds are polluted by organic and inorganic material from human activities. The study on coliform bacteria concentration in Okpon River,
ENI, DEVALSAM IMOKE, IGELLE E. I.
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Estimation of the occurrence, severity, and volume of heartwood rot using airborne laser scanning and optical satellite data

open access: yesEuropean Journal of Remote Sensing, 2023
Rot in commercial timber reduces the value of the wood substantially and estimating the occurrence, severity, and volume of heartwood rot would be a useful tool in decision-making to minimize economic losses.
Endre Hansen   +5 more
doaj   +1 more source

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