Results 21 to 30 of about 3,297,912 (305)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Environmental Sampling Drone

open access: yes, 2019
Large pits filled with contaminated water are a product of many mining operations. Collecting water samples from mine pits is a dangerous task that requires skill and caution as the body of water is surrounded by steep inclines. A drone offers a much safer and quicker alternative.
Perkins, Cody   +3 more
openaire   +2 more sources

Metaproteomics for analysis of microbial function in the environment [PDF]

open access: yes, 2007
This report briefly describes the approach of using proteomic analyses to examine protein expression directly from environmental samples (termed metaproteomics).
Bond, PL, Wexler, M
core  

Aquatic Effects of a Localized Oil Spill on Lake Conway, AR and Its Tributaries [PDF]

open access: yes, 2015
Oil spills, no matter where they occur, elicit environmental concern and avoiding these disasters should be a priority. Old pipelines that are not regularly maintained and carry large amounts of crude oil long distances are of particular concern.
Bouldin, J. L., Kennon, M. E.
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Sampling environmental DNA from trees and soil to detect cryptic arboreal mammals [PDF]

open access: green, 2022
Michael C. Allen   +8 more
openalex   +1 more source

Preferences and values for forests and wetlands: a comparison of farmers, environmentalists, and the general public in Australia [PDF]

open access: yes, 2005
[Abstract]: Over the past decades, a trend towards environmental concern has been measured in general population samples. Natural resource management is a complex area in which multiple stakeholders compete for their different views to be heard ...
Winter, Caroline
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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