Results 171 to 180 of about 12,033,968 (396)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Recent Advances in the Fabrication and Environmental Science Applications of Cellulose Nanofibril-Based Functional Materials. [PDF]

Materials (Basel), 2021
Zhang L, Guo L, Wei G.
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Environmental Sciences Division annual progress report for period ending September 30, 1978. Environmental Sciences Division publication No. 1280

, 1979
S.I. Auerbach, D.E. Reichle, E.G. Struxness   +2 more
openalex   +2 more sources

Symposium on Target Organ Toxicity: Nervous System. Environmental Health Sciences (NIEHS), Raleigh, North Carolina, October 19-20, 1977. [PDF]

, 1978

openalex   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Ecotrons: Powerful and versatile ecosystem analysers for ecology, agronomy and environmental science. [PDF]

Glob Chang Biol, 2021
Roy J, Rineau F, De Boeck HJ, Nijs I, Pütz T, Abiven S, Arnone JA, Barton CVM, Beenaerts N, Brüggemann N, Dainese M, Domisch T, Eisenhauer N, Garré S, Gebler A, Ghirardo A, Jasoni RL, Kowalchuk G, Landais D, Larsen SH, Leemans V, Le Galliard JF, Longdoz B, Massol F, Mikkelsen TN, Niedrist G, Piel C, Ravel O, Sauze J, Schmidt A, Schnitzler JP, Teixeira LH, Tjoelker MG, Weisser WW, Winkler B, Milcu A.   +35 more
europepmc   +1 more source

Environmental Science Institute Develops Water Sampler

, 1972
J. L. Kline
openalex   +1 more source

ENVIRONMENTAL SCIENCE

, 2023
openaire   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source