Results 201 to 210 of about 11,766,032 (363)

Knothole December 1, 1993 Vol 46 No 12 [PDF]

open access: yes, 1993
The mission of The Knothole publication is to provide its readers with writings that are both stimulating and contemporary; to inform its students of clubs, events, and off-campus happenings; to challenge a world driven by progress to uncover the truth ...
SUNY College of Environmental Science and Forestry
core   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

A Survey of Foundation Models for Environmental Science [PDF]

open access: yesarXiv
Modeling environmental ecosystems is essential for effective resource management, sustainable development, and understanding complex ecological processes. However, traditional methods frequently struggle with the inherent complexity, interconnectedness, and limited data of such systems.
arxiv  

Knothole November 9, 1981 Vol 32 No 9 [PDF]

open access: yes, 1981
The mission of The Knothole publication is to provide its readers with writings that are both stimulating and contemporary; to inform its students of clubs, events, and off-campus happenings; to challenge a world driven by progress to uncover the truth ...
SUNY College of Environmental Science and Forestry
core   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

open access: yesFEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He   +5 more
wiley   +1 more source

Knothole November 2, 1981 Vol. 32 No. 8 [PDF]

open access: yes, 1981
The mission of The Knothole publication is to provide its readers with writings that are both stimulating and contemporary; to inform its students of clubs, events, and off-campus happenings; to challenge a world driven by progress to uncover the truth ...
SUNY College of Environmental Science and Forestry
core   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Ecotrons: Powerful and versatile ecosystem analysers for ecology, agronomy and environmental science. [PDF]

open access: yesGlob Chang Biol, 2021
Roy J   +35 more
europepmc   +1 more source

Knothole April 5, 1995 Vol 47 No 23 [PDF]

open access: yes, 1995
The mission of The Knothole publication is to provide its readers with writings that are both stimulating and contemporary; to inform its students of clubs, events, and off-campus happenings; to challenge a world driven by progress to uncover the truth ...
SUNY College of Environmental Science and Forestry
core   +1 more source

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