FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Multilinguismo nas ciências ambientais: Ahora ya! (Multilingualism in environmental sciences: it's about time!). [PDF]
Ambio, 2014 Root-Bernstein M, Ladle RJ.
europepmc +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Impact of the Diamond Light Source on research in Earth and environmental sciences: current work and future perspectives. [PDF]
Philos Trans A Math Phys Eng Sci, 2015 Burke IT +5 more
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
ILSI Health and Environmental Sciences Institute (HESI), global leader in advancing translational science to create science-based solutions for a sustainable, healthier world. [PDF]
Genes Environ, 2015 Takei A.
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Electron spin resonance. Part two: a diagnostic method in the environmental sciences. [PDF]
Sci Prog, 2011 Rhodes CJ.
europepmc +1 more source
A Special Issue: Geomathematics in practice: Case studies from earth- and environmental sciences – Proceedings of the Croatian-Hungarian Geomathematical Congress, Hungary 2015 [PDF]
, 2016 István Gábor Hatvani, Janina Horváth
openalex +1 more source