Results 171 to 180 of about 17,235,601 (296)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Reporting Chemical Data in the Environmental Sciences. [PDF]

ACS Environ Au
Baskaran S, Chirsir P, Joudan S, Wolf R, Bolton EE, Thiessen PA, Schymanski EL.   +6 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Using Open Science Tools to Teach Environmental Sciences. [PDF]

Ecol Evol
Zuliani M, Lortie CJ.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Opening doors to physical sample tracking and attribution in Earth and environmental sciences. [PDF]

Sci Data
Damerow JE, Raia NH, Stanley V, Choe S, Borton MA, Byers N, Cassidy ER, Cholia S, Edmunds R, Forbes B, Forrest K, Goldman AE, Kunze J, Lafia S, Lehnert K, McIntyre-Redden M, Naples R, O'Ryan D, Parker C, Plomp E, Powers-McCormack B, Ramdeen S, Richard S, Thessen A, Thompson CW, Vieglais D, Vrouwenvelder K, Wood-Charlson EM, Wyborn L, Reddy TBK, Thomer AK.   +30 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Assessing semantic interoperability in environmental sciences: variety of approaches and semantic artefacts. [PDF]

Sci Data
Di Muri C, Pulieri M, Raho D, Muresan AN, Tarallo A, Titocci J, Nestola E, Basset A, Mazzoni S, Rosati I.   +9 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Mapping large bodies of research in environmental sciences: insights from compiling evidence on the recovery and reuse of nutrients found in human excreta and domestic wastewater. [PDF]

Environ Evid
Harder R.
europepmc   +1 more source