Results 31 to 40 of about 757,045 (213)

Sous influences : construction et fragilisation de la sensibilité environnementale des habitants des barrios à Santo Domingo

Développement Durable et Territoires, 2021
Considered to have no ecological awareness, the inhabitants of the barrios are accused of harming the urban ecosystem. In this sense, two solutions have often been provided: on the one hand, urban interventions mobilize a hygienic and sanitary approach ...
Darysleida Sosa Valdez
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Child and parent behavioral and physiological reactivity to threat and distress predict children's proactive and reactive aggression

Frontiers in Child and Adolescent Psychiatry
IntroductionThreat reactivity has been linked to early manifestations of aggressive behavior, with prior research suggesting that parenting can moderate the relation between a child's psychophysiological reactivity and antisocial behavior.
Kostas A. Fanti, Antonios I. Christou, Melina Nicole Kyranides, Ioannis Mavrommatis, Georgia Soursou, Nicholas D Thomson   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

An R package "VariABEL" for genome-wide searching of potentially interacting loci by testing genotypic variance heterogeneity

BMC Genetics, 2012
Background Hundreds of new loci have been discovered by genome-wide association studies of human traits. These studies mostly focused on associations between single locus and a trait. Interactions between genes and between genes and environmental factors
Struchalin Maksim V, Amin Najaf, Eilers Paul HC, van Duijn Cornelia M, Aulchenko Yurii S   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

School Managers Perceptions towards Energy Efficiency and Renewable Energy Sources

International Journal of Renewable Energy Development, 2021
Global economic growth is accompanied by increased energy demand, thus conventional fuels such as coal, oil and gas, which are the primary energy sources, are gradually being depleted.
Dimitrios Drosos, Grigorios L. Kyriakopoulos, Stamatios Ntanos, Androniki Parissi   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

More than just a tree: Ecolinguistics and responses to the felling of ‘Hadrian’s tree’

Russian Journal of Linguistics, 2023
In the current climate ecolinguistic research has arguably never been more important, as its basic premises regard the survival of life on Earth and key philosophical questions hitherto under-acknowledged by mainstream science.
Douglas Mark Ponton
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source