Results 161 to 170 of about 18,563,074 (305)
152 p.This sourcebook contains 367 graphics, most of which are computer generated and indicate current conditions and trends in the environment of the United States.
Council on Environmental Quality
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Efficient stem cell-derived mouse embryo models for environmental studies. [PDF]
Jorgensen V +10 more
europepmc +1 more source
CONCEPTUALIZING AND QUANTIFYING THE ENVIRONMENTAL IMPACTS OF BIOLOGICAL PRODUCTION SYSTEMS
Increasing the amount of food produced while simultaneously reducing the environmental impacts of agriculture is one of the most pressing challenges facing humanity.
McGrath, Keegan
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
<i>Malassezia</i> in environmental studies is derived from human inputs. [PDF]
Rahimlou S, Amend AS, James TY.
europepmc +1 more source

