Results 61 to 70 of about 588,114 (308)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Известия высших учебных заведений: Геология и разведка, 2016 Currently an ecological basis of the urban planning documentation is performed during engineering and environmental surveys, which in the development of urban underground space should ensure the optimality of design decisions on environmental ...
E. Yu. Kulikova
doaj +2 more sources
City footprints and SDGs provide untapped potential for assessing city sustainability
Nature Communications, 2021 Whether or not a city achieves absolute sustainability is difficult to assess with existing frameworks. Here the authors, in a review, show that a further integration of consumption-based accounting and benchmarking is necessary to aid the monitoring and
Thomas Wiedmann, Cameron Allen
doaj +1 more source
Requirements: The Key to Sustainability [PDF]
, 2015 Software's critical role in society demands a paradigm shift in the software engineering mind-set. This shift's focus begins in requirements engineering.
Becker, Christoph +7 more
core +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Materials Today SustainabilityThis study critically explores the integration of Life-Cycle Assessment (LCA) within civil engineering as a strategy to enhance the sustainability of infrastructure projects.
Ali Akbar Firoozi +2 more
doaj +1 more source
Achieving sustainable construction in the developing countries Of Southeast Asia [PDF]
, 2006 Sustainable construction is a way for the building industry to move towards achieving sustainable development, taking into account environmental, socioeconomic and cultural issues.
Arman Ali, Zainab +2 more
core
Investment in Sustainable Development: A UK Perspective on the Business and Academic Challenges [PDF]
, 2009 There are many legislative, stakeholder and supply chain pressures on business to be more ‘sustainable’. Universities have recognised the need for graduate knowledge and understanding of sustainable development issues.
Garland, Nigel P. +3 more
core +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source