Results 161 to 170 of about 14,242,361 (316)
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
A case study of watershed-based pollution trading in the Assabet River Basin [PDF]
, 1999 Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 1999.Includes bibliographical references.by Steven L.
McGinnis, Steven L. (Steven Lee), 1974-
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Concepts of testing for collocated and distributed software development [PDF]
, 2000 Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2000.Includes bibliographical references (leaves 89-91).by Kenward Ma.M ...
Ma, Kenward (Kenward Kam Wing), 1977-
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
A price prediction method In real estate market
, 2016 Thesis: S.M., Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 2016.Cataloged from PDF version of thesis.Includes bibliographical references (pages 71-75).Current housing price prediction usually employs hedonic ...
Li, Heng, S.M. Massachusetts Institute of Technology
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Maintenance of cable-stayed bridges [PDF]
, 2000 Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2000.Includes bibliographical references (leaf 63).by Shin-Gia Chen.M ...
Chen, Shin-Gia, 1973-
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Impact of environmental regulation, energy technology innovation on population health
BMC Public HealthBackground Environmental regulations and energy technology innovation play crucial roles in promoting environmental construction, enhancing ecological environment quality, and improving residents’ health and well - being. Method This study integrated the
XiFeng Yang
doaj +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source