Results 101 to 110 of about 436,578 (316)

Computational Approaches for the Prediction of Environmental Transformation Products: Chlorination of Steroidal Enones. [PDF]

Environ Sci Technol, 2021
Knutson CJ, Pflug NC, Yeung W, Grobstein M, Patterson EV, Cwiertny DM, Gloer JB.   +6 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Techniques of repair, the circulation of knowledge, and environmental transformation: Towards a new history of transportation. [PDF]

Hist Sci, 2023
Margócsy D, Brazelton MA.
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Farmers’ soil knowledge, fertility management logic and its linkage with scientifically analyzed soil properties in southern Ethiopia

Agriculture & Food Security, 2017
Background Farmers’ locally have acquired knowledge from generations of experience and experimentation that fit local conditions. Yet, the scientific approach less used farmers’ soil knowledge (FSK) and site-specific soil information.
Fanuel Laekemariam, Kibebew Kibret, Tekalign Mamo   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Acacia dealbata seeds as a sustainable nutritional resource: high-value nutrients from a hardy, underutilized species

Applied Food Research
Acacia dealbata is a plant native to southeastern Australia that has traditionally been used by Aboriginal Australians as a source of food, food additives, and natural remedies. The seeds of A. dealbata were ground into a flour for making bread. However,
Md Sanowar Hossain, Matthew K. Jago, Jacqui L. Adcock, Damien L. Callahan   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Intervention and research progress of gut microbiota-immune-nervous system in autism spectrum disorders among students

Frontiers in Microbiology
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in social interaction and communication, repetitive and stereotyped behaviors, restricted interests, and sensory abnormalities.
Min Zhou, Baoming Niu, Jiarui Ma, Yukang Ge, Yanxin Han, Wenrui Wu, Changwu Yue   +6 more
doaj   +1 more source

Pedo-environmental evolution and agricultural landscape transformation

Italian Journal of Agronomy, 2009
Landscapes represent the stage setting of the ecosystem, the great theatre where the evolution of the environment, the changing of things and plant and animal life are played out; the diversity of landscapes derives from the combination, over time, of ...
Gilmo Vianello, Livia Vittori Antisari
doaj   +1 more source