Results 91 to 100 of about 8,716,422 (261)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
, 1992 This record contains two environmental education newsletters published by the township of Belmar. Topics covered in the first newsletter include the environmental commission, beachfront, recycling, and lakes. The second has articles on recycling, dunes,
core +1 more source
Arachnologische Mitteilungen, 2016 Epigaeic invertebrates were sampled at non-invaded (‘Indigenous Forest’ and ‘Indigenous Grassland’) and alien-invaded (‘Eucalyptus’ and ‘Mixed Alien’) sub-sites in the Nduli and Luchaba Nature Reserves using pitfall traps.
Niba, Augustine S., Yekwayo, Inam
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
ENVIRONMENTAL AND PSYCHOLOGICAL VARIABLES ASSOCIATED WITH JOB PERFORMANCE IN THE NEWSILIPALITS AN APPLIED STUDY ON CAIRO GOVERNMENT [PDF]
Journal of Environmental ScienceThe current research aimed to identify the environmental and psychological variables that have an impact on the job performance of the local sector. The necessary tool was designed and applied to the research sample, a group of employees in the General ...
Eman Ahmed +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Economy and Environmental Problems in the Mexican Coastal States [PDF]
A canonical correspondence analysis (CCA) for environmental and economic variables was performed for 17 Mexican coastal states. The ordination method allowed us to identify three groups, namely hydroelectric energy generation (I), pollution (II) and ...
Luis F. Beltrán Morales +4 more
core
Effects of seasonal meteorological variables on E. coli persistence in livestock faeces and implications for environmental and human health [PDF]
, 2016 Agriculture contributes significant volumes of livestock faeces to land. Understanding how faecal microbes respond to shifts in meteorological patterns of contrasting seasons is important in order to gauge how environmental (and human health) risks may ...
Oliver, David M. +2 more
core +1 more source