Results 151 to 160 of about 819,369 (267)

Machine learning and dose response effect models: an integrated approach to analyze the association between environmental variables and Cuneo Emergency Department admissions for Acute Otitis Media (2007-2015). [PDF]

Int J Biometeorol
Rondinone M, Condemi V, Gestro M, Telesca V.   +3 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Modelling the impact of climatic and environmental variables on malaria incidence in Tanzania: Implications for achieving the WHO's 2030 Targets. [PDF]

PLOS Glob Public Health
Lutambi AM, Emidi B, Mbuya FG, Ryoba M, Sagamiko TD, Hugo AK, Mbalawata IS.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Impacts of key environmental variables on suitable cultivation and flavonoid accumulation in Pueraria montana var. lobata under climate change in China. [PDF]

PLoS One
Li Y, Li Y, Chen Z, Yang X, Zuo Q, Hu M, Li S, Teng X, Cheng C, Cheng Q.   +9 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Environmental Suitability of the Sicilian Pond Turtle (<i>Emys trinacris</i>): An Approach Based on Bioclimatic and Environmental Variables for the Conservation of Sicilian Endemism. [PDF]

Animals (Basel)
Lo Valvo M, Orecchio G, Barone MC, Virgilio V, Faraone FP.   +4 more
europepmc   +1 more source

Database on environmental variables

Spatial and temporal resolved database of primary production rates temperature salinity light intensities nutrient concentrations glacier ...
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Corrigendum: Dynamics of CO2 fluxes and environmental responses in a poplar plantation

Frontiers in Environmental Science
Mengyu Ge, Mengyu Ge, Weifeng Wang, Honghua Ruan, Guobing Wang, Shuang Zhang, Shuiqiang Yu   +6 more
doaj   +1 more source