Results 41 to 50 of about 5,003,459 (305)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Monitoring the Interannual Spatiotemporal Changes in the Land Surface Thermal Environment in Both Urban and Rural Regions from 2003 to 2013 in China Based on Remote Sensing

Advances in Meteorology, 2019
The thermal environment is closely related to human well-being. Diurnal and seasonal variations in surface urban heat islands (SUHIs) have been extensively studied. Nevertheless, interannual changes in SUHIs as well as in land surface temperatures (LSTs)
Yuanzheng Li, Lan Wang, Liping Zhang, Qing Wang   +3 more
doaj   +1 more source

TATA KELOLA TAMAN NASIONAL MERU BETIRI (TNMB) BERDASARKAN ASPEK GEOLOGI LINGKUNGAN

JTSL (Jurnal Tanah dan Sumberdaya Lahan), 2020
Meru Betiri National Park (TNMB) is a natural conservation area related to land use that impact on the environment. Land-use suitability with land capability is essential so that the impact of the geological environment that can occur can be reduced and ...
Januar Aziz Zaenurrohman, Januar Fery Irawan, Indra Permanajati, Sachrul Iswahyudi   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Green zoning regulation under price discrimination [PDF]

Zbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2017
This study aims to examine urban zoning within a linear city in a Bertrand duopolistic competition framework with price discrimination and linear transportation costs.
Hamid Hamoudi, María J. Moral
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Exploring the nexus between renewable energy, climate and disaster risk reduction, and land use planning: The case of Paete, Laguna, Philippines [PDF]

E3S Web of Conferences
Renewable energy presents a plausible strategy for empowering communities by achieving energy self-reliance and security while ensuring balanced economic growth and environmental protection amidst global climate change, such is the case in the ...
Reyes Edgar M., Magpantay Angelica T.
doaj   +1 more source