Results 91 to 100 of about 4,457,752 (339)

ENVIRONMENTAL UNCERTAINTY AND THE TIMING OF ENVIRONMENTAL POLICY [PDF]

open access: yesNatural Resource Modeling, 2004
ABSTRACT. This paper shows that the timing of an investment to reduce the emissions of a stock pollutant under environmental uncertainty depends on the specification of uncertainty, on its level, and on the presence of a lower reflecting barrier for the stock pollutant.
openaire   +1 more source

Conceptualizing a corporate environmentalism model

open access: yes, 1995
Environmental legislation now looms large in the backdrop of corporate strategy. However, there is still little theoretical work on corporate environmentalism.
Josephine Chinying Lang
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Industrialism vs Environmentalism [PDF]

open access: yes, 2014
This study is about the struggle in our society between industrialism and environmentalism. Environmentalists point out the industrialism is destroying the environment at a rapid pace.
Sun, Isaiah
core  

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The religion of Environmentalism [PDF]

open access: yes, 2015
From Defining Ideas, available online: http://www.hoover.org/research/religion-environmentalism.
Thornton, Bruce
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Ecological art : counterculture environmentalism in the arts of the 1960s and 70s

open access: yes, 2019
Thesis (M.A.)Department of HistoryIntroduction : an American counterculture and a new environmentalism -- Green words : literary appearances of counterculture environmentalism -- Artists in the land : land art sculpture and countercultural ...
Rivers, Nathan
core  

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