Results 131 to 140 of about 12,746 (312)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Environmentalism/Postmodernism

open access: yes, 2012
This presentation explores the meaning of environmentalism and postmodernism in a political science ...
Ogunniya, Toby
core  

Surging Environmentalism in Japan : Back to the Root [PDF]

open access: yes, 1997
"The major objective of this paper is to examine the complex phenomenon of the interrelationship among several conditions that have transformed Japanese environmentalism in its socio-economic situations, political activities, cultural contexts and ...
満田, 久義
core  

From ‘zombies’ to ‘coyotes’: environmentalism where we are

open access: yes, 2010
Environmentalism is in trouble. Some denounce it for being 'depressing and dowdy'; others have announced its 'death'. Environmentalism faces three problems: the disconnection of 'the environment' as an intellectual concept from popular understandings ...
Jon Anderson, Anderson, Jonathan Mark
core   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Working for Health in the Anthropocene: The Environmental Imagination in the Establishment of Occupational Therapy, 1890–1920

open access: yesHistories
By the end of the nineteenth century, the view of labour as control of the environment for human benefit was being re-evaluated. In the United States, the conservation movement of the Progressive era (1890–1920) brought new attention to the problem of ...
Mark Hudson
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

From liberal paralysis to green republican resolution? Conceptualising, illustrating, and addressing problems of governability in eco-social politics

open access: yesFrontiers in Political Science
The phenomenon of ungovernability is by no means new and had already been described 50 years ago in the literature, but awareness of its importance has only recently been reawakened.
Veith Selk, Niklas Klüh
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Environmental ethics: An essence for environmental protection

open access: yesEnvironment Conservation Journal, 2009
With the rapid  and unplanned  industrialization  the human  society is  facing  different  environmental problems due to variety of destructing  activities.  There is  an urgent need to stop further degradation of nature or at least keep it under control.
openaire   +2 more sources

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