Results 111 to 120 of about 3,196,986 (319)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
McRae, Lee, Learning Environments
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Climate change and broiler production
Climate change has emerged as a significant occurrence that adversely affects broiler production, especially in tropical climates. Broiler chickens, bred for rapid growth and high meat production, rely heavily on optimal environmental conditions to ...
Oyegunle Emmanuel Oke +6 more
doaj +1 more source
Yield and quality of hybrid tomato grafted and cultivated under shade mesh and greenhouse
The objective was to determine the yield, fruit quality and root development of four grafted tomato hybrids grown under anti-aphid mesh cover and greenhouse.
Antonio Reyes-Cabrera +5 more
doaj +1 more source
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
McRae, Lee, Learning Environments
core
Hyper-selection in dynamic environments [PDF]
This article is posted here with permission from IEEE - Copyright @ 2008 IEEEIn recent years, several approaches have been developed for genetic algorithms to enhance their performance in dynamic environments.
Yang, S +5 more
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
McRae, Lee, Learning Environments
core
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source

