Results 161 to 170 of about 11,563,248 (344)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

When does accounting for gene-environment interactions improve complex trait prediction? A case study with Drosophila lifespan. [PDF]

G3 (Bethesda)
Morgante F, Tiezzi F.
europepmc   +1 more source

Trading environments [PDF]

British Dental Journal, 2008
openaire   +2 more sources

Risky families: family social environments and the mental and physical health of offspring.

Psychological bulletin, 2002
R. Repetti, Shelley E. Taylor, T. Seeman
semanticscholar   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Reply to Cecchi and Palminteri: On the need to model temporal variation in learning rates. [PDF]

Proc Natl Acad Sci U S A
Godara P.
europepmc   +1 more source

Local environments [PDF]

, 2011
Buck, N, Rabe, B
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Identification of high-yielding and stable Egyptian soybean genotypes for breeding across varied environments. [PDF]

BMC Plant Biol
Waly FE, Zied AAA, Mourad KHA, Abdelghany M.   +3 more
europepmc   +1 more source

Organizations and Environments

, 1979
Howard E. Aldrich
semanticscholar   +1 more source