Results 191 to 200 of about 11,563,248 (344)

Adaptive versus non‐adaptive phenotypic plasticity and the potential for contemporary adaptation in new environments

, 2007
C. Ghalambor, J. McKay, Scott P Carroll, D. Reznick   +3 more
semanticscholar   +1 more source

Role of proline under changing environments

Plant Signalling & Behavior, 2012
S. Hayat, Qaiser Hayat, M. Alyemeni, Arif Shafi Wani, J. Pichtel, A. Ahmad   +5 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Predicting enviromically adapted varieties with big data. [PDF]

Genome Biol
Gogna A, Kamali B, Wimmer V, Schmidt RH, Rezaei EE, Eckhoff WM, Reif JC, Zhao Y.   +7 more
europepmc   +1 more source

Evolution of life in urban environments

Science, 2017
Marc T. J. Johnson, J. Munshi-South
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Hybrid kernels integrating genomic and multispectral data improve wheat genomic prediction accuracy. [PDF]

Plant Genome
Montesinos-López OA, Martínez-Regalado JA, Murillo-Avalos CL, Herr AW, Montesinos-López A, Delgado-Enciso I, Cuevas J, Crossa J, Carter AH.   +8 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Real-world Speech Communication Experiences of Cochlear Implant Users. [PDF]

Otol Neurotol Open
Titanji BN, Moberly AC, Tamati TN.
europepmc   +1 more source

Glacial Environments

, 2012
Netto, Renata G., Benner, Jacob S., Buatois, Luis A., Uchman, Alfred, Mángano, M. Gabriela, Ridge, John C., Kazakauskas, Vaidotas, Gaigalas, Algirdas   +7 more
openaire   +2 more sources