Results 191 to 200 of about 3,196,986 (319)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

How storey configuration and number of transition points shape opportunities for outdoor access in residential care facilities: implications for age-friendly environments. [PDF]

BMC Geriatr
Liljegren M, Bengtsson A, Nordin S, Lindahl G, Wijk H.   +4 more
europepmc   +1 more source

Nanoparticles and the Environment [PDF]

Journal of the Air & Waste Management Association, 2005
Judith C. Chow, John G. Watson, Nora Savage, C. Jack Solomon, Yung-Sung Cheng, Peter H. McMurry, Lisa M. Corey, Gretchen M. Bruce, Richard C. Pleus, Richard C. Pleus, Pratim Biswas, Chang-Yu Wu   +11 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Mixed Reality as an Environment for Reaction Speed Assessment in Physically Active Young Adults: Measurement Reliability and Participant Experience Compared with Immersive Virtual Reality. [PDF]

Sensors (Basel)
Polechoński J, Dębska-Janus M, Kostorz K, Rozpara M, Zając-Gawlak I, Nawrocka A, Cholewa J.   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Editorial: Microbiology of radioactive environments

Frontiers in Microbiology
Sudhir K. Shukla, Sudhir K. Shukla, Rok Tkavc, Rok Tkavc, Haitham Sghaier, Haitham Sghaier   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Hybrid path planning for mobile robots in complex environments: Fusing improved BI-RRT and enhanced DWA. [PDF]

PLoS One
Wang G, Sun H, Feng Z.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source