Results 31 to 40 of about 361,422 (265)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

The influence of soil types and agricultural management practices on soil chemical properties and microbial dynamics

Frontiers in Sustainable Food Systems
Soil provides essential nutrients for plant growth, but excess salts hinder development, making crops more vulnerable under climate change conditions. Soil microorganisms play a significant role in nutrient cycling.
Tanuja Poonia, Madhu Choudhary, Manish Kakraliya, Manish Kakraliya, Bharti Dixit, Hanuman Sahay Jat, Hanuman Sahay Jat   +6 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Metabolomics and physio-chemical analyses of mulberry plants leaves response to manganese deficiency and toxicity reveal key metabolites and their pathways in manganese tolerance

Frontiers in Plant Science
IntroductionManganese (Mn) plays a pivotal role in plant growth and development. Aside aiding in plant growth and development, Mn as heavy metal (HM) can be toxic in soil when applied in excess. Morus alba is an economically significant plant, capable of
Jianbin Li, Jianbin Li, Michael Ackah, Michael Ackah, Frank Kwarteng Amoako, Zipei Cui, Zipei Cui, LongWei Sun, LongWei Sun, Haonan Li, Haonan Li, Victor Edem Tsigbey, Victor Edem Tsigbey, Mengdi Zhao, Weiguo Zhao, Weiguo Zhao   +15 more
doaj   +1 more source

Control of biogas production process by enzymatic and fluorescent image analysis

Biotechnology & Biotechnological Equipment, 2018
The process of methanogenesis, which is in the essence of the widely distributed technologies for biogas production, is slow, has multiple steps and occurs under anaerobic conditions.
Nora Dinova, Mihaela Belouhova, Irina Schneider, Jelyaz Rangelov, Yana Topalova   +4 more
doaj   +1 more source

Alternaria alternata Isolated from Infected Pears (Pyrus communis) in Italy Produces Non-Host Toxins and Hydrolytic Enzymes as Infection Mechanisms and Exhibits Competitive Exclusion against Botrytis cinerea in Co-Infected Host Fruits

Journal of Fungi, 2023
Alternaria alternata is one of the most devastating phytopathogenic fungi. This microorganism causes black spots in many fruits and vegetables worldwide, generating significant post-harvest losses. In this study, an A.
Stefany Castaldi, Jesús G. Zorrilla, Claudia Petrillo, Maria Teresa Russo, Patrizia Ambrosino, Marco Masi, Alessio Cimmino, Rachele Isticato   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Roles of Mitochondrial SIRT4 in Cellular Metabolism

Frontiers in Endocrinology, 2019
Sirtuins comprise a family of nicotinamide adenine dinucleotide (NAD+)-dependent lysine deacylases that regulate the life span, aging, and metabolism. Seven sirtuin family members (SIRT1-7) have been identified in mammals, including humans.
Zheying Min, Zheying Min, Jiangman Gao, Yang Yu   +3 more
doaj   +1 more source