Results 181 to 190 of about 671,790 (405)

Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model

open access: yesAdvanced Therapeutics, EarlyView.
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika   +7 more
wiley   +1 more source

The Serum Amyloid β Level in Multiple Sclerosis: A Case- Control Study

open access: yesCaspian Journal of Neurological Sciences, 2017
Background: Multiple sclerosis (MS) is one of the most common autoimmune diseases in adults that cause disability in patients. Different studies were conducted on more rapid diagnosis of the disease such as measuring serum or cerebrospinal fluid (CSF ...
Masoud Etemadifar   +3 more
doaj  

Emerging Therapeutic Strategies for Hearing Loss

open access: yesAdvanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han   +9 more
wiley   +1 more source

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

open access: yesAdvanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang   +16 more
wiley   +1 more source

Standardisation of an indirect enzyme-linked immunosorbent assay for the detection [PDF]

open access: yesVeterinaria Italiana, 2011
An indirect enzyme-linked immunosorbent assay (ELISA) was evaluated for the detection of Brucella antibodies in milk from water buffalo (Bubalus bubalis Linnaeus, 1758). The test accuracy was evaluated on milk samples from the Campania Region in Italy. A
Manuela Tittarelli   +4 more
doaj  

Zeolitic Imidazolate Framework-8 offers an anti-inflammatory and antifungal method in the treatment of Aspergillus fungus keratitis in vitro and in vivo [PDF]

open access: yesarXiv
Background: Fungal keratitis is a serious blinding eye disease. Traditional drugs used to treat fungal keratitis commonly have the disadvantages of low bioavailability, poor dispersion, and limited permeability. Purpose: To develop a new method for the treatment of fungal keratitis with improved bioavailability, dispersion, and permeability.
arxiv  

The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels

open access: yesAdvanced Science, EarlyView.
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni   +16 more
wiley   +1 more source

Development of reference ELISA assays for urinary oestrone-3 ¯-glucuronide and pregnanediol-3 ¯-glucuronide using timed urine specimens : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

open access: yes, 1999
Enzyme-linked immunosorbent assays (ELISA) have been developed which measure oestrone glucuronide (E1-3G) and pregnanediol glucuronide (PdG) in timed, diluted urine samples. Measurement of these urinary metabolites allows information to be collected, non-
Binnie, Janette Elizabeth
core  

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