Results 151 to 160 of about 6,233,293 (384)
Clinics in Laboratory Medicine, 1973 Abstract Since Warburg and his associates reported in 1924 that cancer tissue exhibits a greater rate of aerobic glycolysis than normal tissue, there have been numerous efforts to define enzymatic defects in cancer tissue. Attempts have been made to use enzyme assays in the diagnosis of cancer and in following the course of the disease ...
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Liver enzyme alteration: a guide for clinicians
Canadian Medical Association Journal, 2005 ISOLATED ALTERATIONS OF BIOCHEMICAL MARKERS OF LIVER DAMAGE in a seemingly healthy patient can present a challenge for the clinician. In this review we provide a guide to interpreting alterations to liver enzyme levels.
E. Giannini, R. Testa, V. Savarino
semanticscholar +1 more source
Enzyme economy in metabolic networks
, 2014 Metabolic systems are governed by a compromise between metabolic benefit and enzyme cost. This hypothesis and its consequences can be studied by kinetic models in which enzyme profiles are chosen by optimality principles. In enzyme-optimal states, active
Liebermeister, Wolfram
core
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
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SENSITIVITY OF SERUM ENZYME INHIBITORS TO A VARIETY OF CANCER CHEMOTHERAPEUTIC AGENTS 12 [PDF]
, 1951 Frank W. Ellis, Philip M. West
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ENZYMES AND ANTI-ENZYMES OF INFLAMMATORY EXUDATES [PDF]
Journal of Experimental Medicine, 1904 The serum of an inflammatory exudate has the power of inhibiting the action of proteolytic ferments contained in the leucocytes. This anti-enzymotic power is possessed by the blood serum from which it doubtless passes into the exudate. In the later stages of inflammation there is some diminution of this anti-enzymotic action.
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A pH Dependant Switch in DHP Oxidation Mechanism [PDF]
, 2017 Dehaloperoxidase (DHP) is a multifunctional enzyme found in Amphitrite ornata, a sediment-dwelling marine worm. This enzyme possess the structure of a traditional hemoglobin enzyme and serves as the primary oxygen carrier in A.
Fehr, Travis
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Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Environmental MicrobiomeIntroduction Metagenomics, the genomic analysis of all species present within a mixed population, is an important tool used for the exploration of microbiomes in clinical and environmental microbiology.
Josephine Herbert +3 more
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