Results 271 to 280 of about 6,423,279 (401)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Enhanced stability and reusability of recombinant silicatein upon biomimetic metal-organic framework crystallization. [PDF]

Chem Sci
Zhang T, Wang X, Wright JD, Whitehead GFS, Tidey JP, Wong LS, Riddell IA.   +6 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Pancreatic enzyme

Suizo, 2009
openaire   +2 more sources

Hydrolysis kinetics amino acid profiling and antioxidant properties of enzymatic hydrolysates from desalted egg white. [PDF]

Sci Rep
Rungchang S, Sringarm C, Numthuam S, Tosuk N, Thongsuk T, Phinyo M, Winuprasith T, Jiamyangyuen S.   +7 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Designer enzymes [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2011
openaire   +2 more sources

A disulfide redox switch mechanism regulates glycoside hydrolase function. [PDF]

Nat Commun
Martins MP, Martins GH, Fuzita FJ, Spadeto JPM, Miyamoto RY, Colombari FM, Stoffel F, Dolce LG, Santos CRD, Streit RSA, Borges AC, Galinari RH, Yoshimi Y, Dupree P, Persinoti GF, Morais MAB, Murakami MT.   +16 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

FuncFetch: an LLM-assisted workflow enables mining thousands of enzyme–substrate interactions from published manuscripts [PDF]

Nathaniel Smith, Xinyu Yuan, Chesney Melissinos, Gaurav D. Moghe   +3 more
openalex   +1 more source