Results 281 to 290 of about 6,423,279 (401)

Defining the Human Deubiquitinating Enzyme Interaction Landscape

Cell, 2009
M. Sowa, E. Bennett, S. Gygi, J. Harper
semanticscholar   +1 more source

Optimization of solid-state fermentation conditions for high β-galactosidase-producing lactic acid bacteria and its application in low-lactose dairy products. [PDF]

Front Bioeng Biotechnol
Zhang Z.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Enzyme enhancement activity of N-octyl-β-valienamine on β-glucosidase mutants associated with Gaucher disease

, 2007
Ke Lei, Haruaki Ninomiya, Michitaka Suzuki, Takehiko Inoue, Miwa Sawa, Masami Iida, Hiroyuki Ida, Yoshikatsu Eto, Seiichiro Ogawa, Kousaku Ohno, Yoshiyuki Suzuki   +10 more
openalex   +2 more sources

Statistical estimations in enzyme kinetics.

Biochemical Journal, 1961
G. N. Wilkinson
semanticscholar   +1 more source

Substrate cooperativity shapes competitive inhibitor responses in mycobacterial inosine 5'-monophosphate dehydrogenase. [PDF]

J Enzyme Inhib Med Chem
Knejzlík Z, Bulvas O, Dedola M, Štefek M, Nencka R, Pichová I.   +5 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Effect of Feeding Cottonseed Meal With or Without NSP Enzymes on Growth Performance, Blood Biochemistry, Growth-Related Gene Expression, Intestinal Health and Economic Efficiency in Broilers. [PDF]

Vet Med Sci
Saleh AA, Elkhaiat IA, Mansour M, Genedy S, Alhotan RA, Hussein EOS, Galik B, Hakami H, Sami AS, Kamal MA, El-Shall NA, Fawzy S.   +11 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source