Results 301 to 310 of about 3,915,254 (313)

A new view of missense mutations in α-mannosidosis using molecular dynamics conformational ensembles. [PDF]

Protein Sci
Mandl Š, Di Geronimo B, Alonso-Gil S, Grininger C, George G, Ferstl U, Herzog SA, Žagrović B, Nusshold C, Pavkov-Keller T, Sánchez-Murcia PA.   +10 more
europepmc   +1 more source

Generation of Advanced Blood–Brain Barrier Spheroids Using Human‐Induced Pluripotent Stem Cell‐Derived Brain Capillary Endothelial‐Like Cells

Advanced Biology, EarlyView.
In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt, Sabrina Oerter, Evelin Reitenbach, Sabine Gätzner, Alevtina Höchner, Heinz‐Georg Jahnke, Jörg Piontek, Winfried Neuhaus, Andreas Brachner, Marco Metzger, Antje Appelt‐Menzel   +10 more
wiley   +1 more source

Metronidazole Activation by a Deeply Entangled Dimeric Malic Enzyme in <i>Entamoeba histolytica</i>. [PDF]

Pathogens
Chakrabarty A, Dutta D, Baidya M, Dutta A, Das AK, Ghosh SK.   +5 more
europepmc   +1 more source

Preventive Effect of Metformin in Radiation‐Induced Xerostomia

Advanced Biology, EarlyView.
Head and neck cancer patients who received radiotherapy complain of severe dry mouth due to damage to the salivary glands. Metformin is an antidiabetic drug, but its radio‐protective effect has been reported. It is confirmed that metformin protects the salivary glands from radiation and provides evidence for the use of metformin in cancer treatment in ...
Sungryeal Kim, Jeong‐Mi Kim, Eun‐Jeong Jeon, Seo‐Young Park, Jin‐Mi Park, Jeong‐Seok Choi   +5 more
wiley   +1 more source

CatPred: a comprehensive framework for deep learning in vitro enzyme kinetic parameters. [PDF]

Nat Commun
Boorla VS, Maranas CD.
europepmc   +1 more source

Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post‐Assembly Loading

Advanced Biology, EarlyView.
The paper explores the creation and characterization of vesicles through biocatalytic Polymerization‐Induced Self‐Assembly (bioPISA), focusing on achieving size uniformity using centrifugation techniques. It examines the effects of stirring speed on vesicle morphology and analyses the internal polymer‐rich structure using fluorescence correlation ...
Andrea Belluati, Adrian Bloch, Kaloian Koynov, Mariana Müller Nieva, Mohadeseh Bagherabadi, Annette Andrieu‐Brunsen, Harald Kolmar, Nico Bruns   +7 more
wiley   +1 more source

The Purification and Characterization of a Novel Neutral Protease from <i>Volvariella volvacea</i> Fruiting Bodies and the Enzymatic Digestion of Soybean Isolates. [PDF]

J Fungi (Basel)
Xu B, Li Z, Guo Q, Zha L, Li C, Yu P, Chen M, Zhao Y.   +7 more
europepmc   +1 more source

RETRACTION: Assessing Wound Complications in Gastroscopy with Streptomyces Protease Enzyme Combined with Shutai. [PDF]

Int Wound J
europepmc   +1 more source

A Cofactor Regeneration System for 2-Aminobutyric Acid Production Based on Combined Cross-Linked Enzyme Aggregates: Utilizing His-Tagged Enzymes With Low-Concentration Calcium Ions as Precipitant. [PDF]

Eng Life Sci
Liu J, Li R, Miao J, Sun H, Chen Q, Song H, Peng H, Chang Y, Luo H.   +8 more
europepmc   +1 more source

Safety evaluation of the food enzyme bacillolysin from the genetically modified Bacillus amyloliquefaciens strain NPR. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Andryszkiewicz M, Cavanna D, Peluso S, Gallo A, De Nijs R, Liu Y.   +19 more
europepmc   +1 more source