Results 331 to 340 of about 6,423,279 (401)
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Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Chemical Society Reviews, 2013Hui Wei, Erkang Wang
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Enzyme–MOF (metal–organic framework) composites
Chemical Society Reviews, 2017Xizhen Lian, Yu Fang, Qi Wang
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Enzyme function prediction using contrastive learning
Science, 2023Enzyme function annotation is a fundamental challenge, and numerous computational tools have been developed. However, most of these tools cannot accurately predict functional annotations, such as enzyme commission (EC) number, for less-studied proteins ...
Tianhao Yu +5 more
semanticscholar +1 more source
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
Nature, 2009Michael A Milhollen +2 more
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Cellular and Molecular Life Sciences, 2001
Diffusion-controlled enzymes are characterized by second-order rate constants in the range 10(8)-10(10) M(-1)s(-1). These values are at the upper end of the observed rates of many enzyme-substrate reactions and have been predicted by theoretical studies on bimolecular reaction in solution.
Stroppolo, ME +3 more
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Diffusion-controlled enzymes are characterized by second-order rate constants in the range 10(8)-10(10) M(-1)s(-1). These values are at the upper end of the observed rates of many enzyme-substrate reactions and have been predicted by theoretical studies on bimolecular reaction in solution.
Stroppolo, ME +3 more
openaire +3 more sources
Hybrid enzymes: manipulating enzyme design
Trends in Biotechnology, 1998Hybrid enzymes are engineered to contain elements of two or more enzymes. Hybrid-enzyme approaches, by taking advantage of the vast array of enzymatic properties that nature has evolved, as well as the strategies that nature has used to evolve them, are becoming an increasingly important avenue for obtaining novel enzymes with desired activities and ...
A E, Nixon, M, Ostermeier, S J, Benkovic
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Comparative Biochemistry and Physiology, 1962
THE determination of mechanisms of enzyme action is among the great problems of modern chemistry (Boyer e t a l . , 1960; Boyer, 1960; Westheimer, 1959). Although not one enzymatic process is today understood, and although no model system has achieved catalytic activity comparable to that of the corresponding enzyme, considerable progress has been made
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THE determination of mechanisms of enzyme action is among the great problems of modern chemistry (Boyer e t a l . , 1960; Boyer, 1960; Westheimer, 1959). Although not one enzymatic process is today understood, and although no model system has achieved catalytic activity comparable to that of the corresponding enzyme, considerable progress has been made
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Current Opinion in Chemical Biology, 2013
Chemospecific and regiospecific modifications of natural products by methyl, prenyl, or C-glycosyl moieties are a challenging and cumbersome task in organic synthesis. Because of the availability of an increasing number of stable and selective transferases and cofactor regeneration processes, enzyme-assisted strategies turn out to be promising ...
Ludger A Wessjohann +3 more
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Chemospecific and regiospecific modifications of natural products by methyl, prenyl, or C-glycosyl moieties are a challenging and cumbersome task in organic synthesis. Because of the availability of an increasing number of stable and selective transferases and cofactor regeneration processes, enzyme-assisted strategies turn out to be promising ...
Ludger A Wessjohann +3 more
openaire +2 more sources
Essays in Biochemistry, 1999
There are many molybdenum-containing enzymes distributed throughout the biosphere. The availability of molybdenum to biological systems is due to the high water solubility of oxidized forms of the metal. Molybdenum enzymes can be grouped on the basis of the structure of the metal centre.
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There are many molybdenum-containing enzymes distributed throughout the biosphere. The availability of molybdenum to biological systems is due to the high water solubility of oxidized forms of the metal. Molybdenum enzymes can be grouped on the basis of the structure of the metal centre.
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Current Opinion in Chemical Biology, 1998
The past year has seen a coming-of-age in DNA enzyme research. Far from being laboratory curiosities, the activities of new DNA enzymes have broadened the known catalytic repertoire of nucleic acid enzymes, provided valuable insights into different mechanistic possibilities open to nucleic acid catalysts, and explored the importance for catalysis of ...
D, Sen, C R, Geyer
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The past year has seen a coming-of-age in DNA enzyme research. Far from being laboratory curiosities, the activities of new DNA enzymes have broadened the known catalytic repertoire of nucleic acid enzymes, provided valuable insights into different mechanistic possibilities open to nucleic acid catalysts, and explored the importance for catalysis of ...
D, Sen, C R, Geyer
openaire +2 more sources