Results 241 to 250 of about 59,667 (304)

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Casein-based film enriched with lignin as a biodegradable substrate for enzyme immobilization. [PDF]

RSC Adv
Dembech E, Sotgiu G, Donnadio A, Buoso S, Dolci G, Nichilo MJFA, Sinisi V.   +6 more
europepmc   +1 more source

IMMOBILIZATION OF ENZYMES: PURIFICATION AND IMMOBILIZATION

, 1989
openaire   +1 more source

The Science of Enzyme Immobilization [PDF]

, 2020
Protocols for simple immobilization of unstable enzymes are plenty, but the vast majority of them, unfortunately, have not reached their massive implementation for the preparation of improved heterogeneous biocatalyst. In this context, the science of enzyme immobilization demands new protocols capable of fabricating heterogeneous biocatalysts with ...
Jose M, Guisan, Fernando, López-Gallego, Juan M, Bolivar, Javier, Rocha-Martín, Gloria, Fernandez-Lorente   +4 more
openaire   +3 more sources

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NMR of Immobilized Enzymes

2020
Solid-state NMR has become the method of choice for the assessment of protein structure for insoluble objects lacking long-range order. In this context, it is apparent that solid-state NMR is also perfectly poised toward the characterization of immobilized proteins. For these systems, it is possible to understand at the atomic level which perturbations,
Cerofolini L., Ravera E., Fragai M., Luchinat C.   +3 more
openaire   +3 more sources

Bacteriolysis by immobilized enzymes

Biotechnology and Bioengineering, 1977
AbstractBacteriolytic enzymes produced by Achromobacter lunatus were immobilized in collagen membrane. Intact bacteria such as Pseudomonas solanacearum, Xanthomonas oryzae, Staphylococcus aureus, and Pseudomonas aeruginosa were lyzed with the bacteriolytic enzyme–collagen membrane. Relative activity of the bacteriolytic enzyme–collagen membrane against
I, Karube, T, Suganuma, S, Suzuki
openaire   +2 more sources

Immobilization of enzymes with polyaziridines

Journal of Biotechnology, 1990
A novel method of enzyme immobilization using a low molecular weight prepolymer of tri-functional aziridines which can immobilize enzymes both by covalent attachment and entrapment within a gel matrix is described. The enzymes are immobilized on a solid support and exhibit an excellent retention of enzymatic activity.
L L, Wood, C S, Cobbs, L, Lantz, L, Peng, G J, Calton   +4 more
openaire   +2 more sources

The bioengineering of immobilized enzymes

Biochimie, 1973
Summary The development of immobilized enzyme reactors depends especially on the efficient production of immobilized enzymes having a long active life under operational conditions. The effect of immobilization by adsorption or covalent-binding on the retention of enzyme activity is described.
M D, Lilly, S P, O'Neill, P, Dunnill
openaire   +2 more sources

Enzyme immobilization on fibrin

Biotechnology and Bioengineering, 1976
The following conclusions can be drawn concerning the utilization of fibrin to immobilized enzyme systems. Fibrin can be used both as a powder or membrane, to covalently immobilize trypsin with retention of activity. Carbon-14 labeled trypsin can be used to estimate the amount of immobilized enzyme on a proteinaceous support.
J G, Dillon, C W, Wade, W H, Daly
openaire   +2 more sources

Immobilized Enzymes and Their Applications

2019
The main goal of enzyme immobilization is the re-use of enzymes for many reaction cycles and extended periods of time. Many novel strategies were developed during the last 20 years. The most common are thec arrier-bound technologies employing synthetic and natural polymers, but also carrier-free enzyme immobilization using chemical crosslinking ...
Cacicedo, Maximiliano Luis, Manzo, Ricardo Martín, Municoy, Sofia, Bonazza, Horacio, Islan, German Abel, Desimone, Martín Federico, Bellino, Martin Gonzalo, Mammarella, Enrique José, Castro, Guillermo Raul   +8 more
openaire   +3 more sources