Processing The Interspecies Quorum-Sensing Signal Autoinducer-2 (AI-2) Characterization Of Phospho-(S)-4,5-Dihydroxy-2,3-Pentanedione Isomerization By LsrG Protein [PDF]
The molecule (S)-4,5-dihydroxy-2,3-pentanedione (DPD) is produced by many different species of bacteria and is the precursor of the signal molecule autoinducer-2 (AI-2).
Lamosa, P.+7 more
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Phenotypic Variation and Bistable Switching in Bacteria [PDF]
Microbial research generally focuses on clonal populations. However, bacterial cells with identical genotypes frequently display different phenotypes under identical conditions.
A Becskei+159 more
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Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. [PDF]
BACKGROUND: Prior studies have shown that switching patients from inducing antiepileptic drugs (AEDs) to lamotrigine, levetiracetam, or topiramate reduces serum lipids and C-reactive protein (CRP). These studies were all of short duration, and some drugs,
Chervoneva, Inna+6 more
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Structure and function of negative feedback loops at the interface of genetic and metabolic networks [PDF]
The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple signal molecules
Andersson, Anna M. C.+3 more
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The mutualistic fungus Piriformospora indica colonizes Arabidopsis roots by inducing an endoplasmic reticulum stress-triggered caspase-dependent cell death [PDF]
In Arabidopsis thaliana roots, the mutualistic fungus Piriformospora indica initially colonizes living cells, which die as the colonization proceeds. We aimed to clarify the molecular basis of this colonization-associated cell death.
Kogel, Karl-Heinz+4 more
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Isolation, screening and characterization of microorganisms with potential for biofuels production [PDF]
Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Rapid global population growth has increased the demand for food and energy supply.
Teixeira, Pedro Jorge Dias, 1989-
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Synthetic biology—putting engineering into biology [PDF]
Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
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Structural modeling and functional analysis of the essential ribosomal processing protease Prp from Staphylococcus aureus [PDF]
In Firmicutes and related bacteria, ribosomal large subunit protein L27 is encoded with a conserved N-terminal extension that is removed to expose residues critical for ribosome function. Bacteria encoding L27 with this N-terminal extension also encode a
Christie, Gail E.+3 more
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Metabolite concentrations, fluxes and free energies imply efficient enzyme usage. [PDF]
In metabolism, available free energy is limited and must be divided across pathway steps to maintain a negative ΔG throughout. For each reaction, ΔG is log proportional both to a concentration ratio (reaction quotient to equilibrium constant) and to a ...
Amador-Noguez, Daniel+6 more
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Controlled overproduction of proteins by lactic acid bacteria [PDF]
Lactic acid bacteria are widely used in industrial food fermentations, contributing to flavour, texture and preservation of the fermented products. Here we describe recent advances in the development of controlled gene expression systems, which allow the
Kleerebezem, Michiel,+3 more
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