Results 111 to 120 of about 2,028,504 (307)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Chirality Selection in Open Flow Systems and in Polymerization
, 2005 As an attempt to understand the homochirality of organic molecules in life, a chemical reaction model is proposed where the production of chiral monomers from achiral substrate is catalyzed by the polymers of the same enatiomeric type. This system has to
Brandenburg A. +9 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
ECUT (Energy Conversion and Utilization Technologies Program). Biocatalysis Project [PDF]
Presented are the FY 1985 accomplishments, activities, and planned research efforts of the Biocatalysis Project of the U.S. Department of Energy, Energy Conversion and Utilization Technologies (ECUT) Program.
core +1 more source
Delignification by Using Alkaline-acid Pretreatment on Bioethanol Production From Rice Straw [PDF]
, 2013 Rice straw as agricultural waste contains cellulose that potentially to produce ethanol. However, it has lignin content that will inhibit the enzyme in converting glucose into ethanol.
Jannah, A. M. (Asyeni)
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Revista Centro Azúcar, 2018 This study shows the use of cellulolytic enzymes Bacillus sp.in enzymatic hydrolysis process and their use in the production of second-generation ethanol.
Jonathan Villavicencio Montoya +5 more
doaj
Thermal inactivation and conformational lock of carbonic anhydrase [PDF]
Carbonic Anhydrase is an enzyme that assists inter-conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Zinc is the key to this enzyme reaction.
امانی, مجتبی +2 more
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Optimization of Physiological Growth Conditions for Maximal Production of L-Asparaginase by Fusarium Species [PDF]
, 2015 L-asparaginase is an enzyme which catalyzes the hydrolysis of amino acid L-asparagine to L-aspartic acid and ammonia. Due to its utility in pharmaceutical as well as food industries, there has been a paramount interest on the production of this enzyme ...
Anil kumar Meghavarnam, . +1 more
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source