Results 41 to 50 of about 2,028,504 (307)

Homozygous disruption of P450 side-chain cleavage (CYP11A1) is associated with prematurity, complete 46,XY sex reversal, and severe adrenal failure [PDF]

, 2005
Disruption of the P450 side-chain cleavage cytochrome (P450scc) enzyme due to deleterious mutations of the CYP11A1 gene is thought to be incompatible with fetal survival because of impaired progesterone production by the fetoplacental unit.
Achermann, JC, Hiort, O, Holterhus, PM, Hoppe, U, Marschke, C, Partsch, CJ, Riepe, FG, Struve, D, Werner, R   +8 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Kinetics of invertase synthesis by Saccharomyces cerevisiae in synthetic medium [PDF]

, 2006
Present investigation deals with optimization of appropriate substrate concentration and incubation temperature both for growth of Saccharomyces cerevisiae and invertase production. Submerged fermentation technique was employed in the present study.
Ikram-ul-Haq, Ikram-ul-Haq, Mukhtar, Hamid   +1 more
core  

Consolidated bioprocessing of starchy substrates into ethanol by industrial Saccharomyces cerevisiae strains secreting fungal amylases [PDF]

, 2015
The development of a yeast strain that converts raw starch to ethanol in one step (called Consolidated Bioprocessing, CBP) could significantly reduce the commercial costs of starch-based bioethanol. An efficient amylolytic Saccharomyces cerevisiae strain
Abdel-Aal, Apiwatanapiwat, Brehmer, Chen, Demirbas, den Haan, Eksteen, Favaro, Favaro, Favaro, Favaro, Favaro, Favaro, Favaro, Hoseney, Hostinová, Jang, Jin, Kang, Khaw, Kim, Kim, Knox, Koutinas, Laemmli, McAllister, Miller, O'Connell, Pejin, Ramachandran, Robertson, Romanos, Rooney, Rooney, Sambrook, Sharp, Sun, Tester, Tester, Thorsen, van Zyl, Viktor, Wang, Yamada, Yamada, Yamada   +45 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Usage of Optimized Least Square SVR to Volume Expansion Estimation of Cement Paste Including Fly Ash and Mgo Expansive Additive [PDF]

Advances in Engineering and Intelligence Systems
The limited hydration capacity and challenges related to delayed expansion prevent fly ash (𝐹𝐴) and 𝑀𝑔𝑂 expansive additive (𝑀𝐸𝐴) from being used significantly.
Mazharul Islam, Sadia Afrin
doaj   +1 more source

Precursors of Cytochrome Oxidase in Cytochrome-Oxidase-Deficient Cells of Neurospora crassa [PDF]

, 1974
Three different cell types of Neurospora crassa deficient in cytochrome oxidase were studied: the nuclear mutant cni-1, the cytoplasmic mutant mi-1 and copper-depleted wild-type cells. * 1.
Ebner E., Ebner E., Edwards D. L., Kiese M., Lansman R., Mason T. L., Mason T. L., Mitchell M. B., Paul K. G., Rifkin M. R., Rubin M. S., Rubin M. S., Schwab A. J., Sebald W., Sebald W., Sebald W., Shakespeare P. G., Warburg O., Weiss H., Werner S., Wohlrab H.   +20 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Degradation of Chloroaromatics: Purification and Characterization of a Novel Type of Chlorocatechol 2,3-Dioxygenase of Pseudomonas putida GJ31 [PDF]

, 1998
A purification procedure for a new kind of extradiol dioxygenase, termed chlorocatechol 2,3-dioxygenase, that converts 3-chlorocatechol productively was developed.
Janssen, Dick B.,, Kasberg, Thomas,, Kaschabek, Stefan R.,, Mars, Astrid E.,, Müller, Dagmar,, Reineke, Walter,   +5 more
core   +2 more sources

Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa. [PDF]

, 2013
Cellulose is recalcitrant to deconstruction to glucose for use in fermentation strategies for biofuels and chemicals derived from lignocellulose. In Neurospora crassa, the transcriptional regulator, CLR-2, is required for cellulolytic gene expression and
Coradetti, Samuel, Glass, N. Louise, Xiong, Yi   +2 more
core   +2 more sources