Results 321 to 330 of about 5,034,587 (402)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Impact of charcoal production on soil micronutrients, enzyme activities, microbial composition, and biomass phosphorus in a derived savannah ecosystem of Nigeria. [PDF]

Sci Rep
Adeyemo AJ, Oluwagbemi IA, Ajiboye WO, Akinnagbe EA, Akande TY, Oyun MB, Awodun MA, Oliveira DMS, Freitas DAF.   +8 more
europepmc   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

Metatranscriptome profile of agricultural microbial communities enriched for plastitrophy. [PDF]

mLife
Olabemiwo FA, Huang Y, Thompson M, Omar H, Kalra S, Arevalo P, Nazzaro V, Cohan FM.   +7 more
europepmc   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Maturation-stage effects of <i>Ziziphus spina-christi</i> fruits and leaves on digestive, inflammatory, antioxidant, and glucose metabolism enzymes in obese rats with type 2 diabetes. [PDF]

RSC Adv
Alshammari AA, Almuzaini NA, Abbès S.
europepmc   +1 more source

Effect of liquefaction temperature and enzymatic treatment on bioethanol production from mixed waste baked products. [PDF]

BMC Biotechnol
Almuhammad M, Kölling R, Einfalt D.
europepmc   +1 more source

Enzymatic craftsmanship in collagen glycosylation. [PDF]

Nat Commun
Ghosh S, Kumar D, Mondal B, Basak T.
europepmc   +1 more source