Results 31 to 40 of about 1,060,604 (333)

Copernicus Downstream Service Supports Nature-Based Flood Defense: Use of Sentinel Earth Observation Satellites for Coastal Needs [PDF]

, 2015
This is a copy of the article published in Sea-Technology Magazine, which the authors have bought the rights to redistribute.With an uncertain future that includes climate change, sea level rise and increasing coastal populations, being able to make ...
Gómez Enri, Jesús, Morris, Edward P., van der Wal, Daphne   +2 more
core   +2 more sources

Dog assisted education in children with rheumatic diseases and adolescents with chronic pain in Germany

GMS Journal for Medical Education, 2023
Objectives: Animal assisted intervention is an increasingly accepted tool to improve human well-being. The present study was performed to assess whether dog assisted education has a positive effect on children suffering from rheumatic disorders with pain
Kiesewetter, Jan, Herbach, Nadja, Landes, Iris, Mayer, Julia, Elgner, Verena, Orle, Karin, Grunow, Alexandra, Langkau, Rovena, Gratzer, Christine, Jansson, Annette F.   +9 more
doaj   +1 more source

A verified equivalent-circuit model for slotwaveguide modulators [PDF]

, 2019
We formulate and experimentally validate an equivalent-circuit model based on distributed elements to describe the electric and electro-optic (EO) properties of travellingwave silicon-organic hybrid (SOH) slot-waveguide modulators.
Freude, Wolfgang, Kieninger, Clemens, Koos, Christian, Kutuvantavida, Yasar, Muradyan, Narek, Randel, Sebastian, Singer, Stefan, Wahlbrink, Thorsten, Yokoyama, Shiyoshi, Zwickel, Heiner   +9 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Safety and efficacy of ketorolac continuous infusion for multimodal analgesia of vaso-occlusive crisis in patients with sickle cell disease

Orphanet Journal of Rare Diseases
Pain is an hallmark of sickle-cell-related acute clinical manifestations as part of acute vaso-occlusive crisis (VOC). In SCD pain has different origins such as vascular or neuropathic pain, which requires multimodal analgesia.
Valeria Maria Pinto, Barbara Gianesin, Salvatore Sardo, Filippo Mazzi, Giammarco Baiardi, Sofia Menotti, Fabio Piras, Sabrina Quintino, Giacomo Robello, Francesca Mattioli, Gabriele Finco, Gian Luca Forni, Lucia De Franceschi   +12 more
doaj   +1 more source

Old MacDonald had a Fyrm, eo, eo, y: two marginal developments of < eo > in Old and Middle English [PDF]

, 2001
'Old MacDonald had a Fyrm, eo, eo, y: two marginal developments of eo in Old and Middle English' uses the new possibilities for linguistic research afforded by the Dictionary of Old English Corpus to help show phonological developments in Old and Middle ...
Hall, Alaric
core   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Knowledge source preferences as determinants of strategic entrepreneurial orientation [PDF]

, 2010
In the knowledge intensive context, firms’ capacity to integrate external and internal sources of knowledge becomes an important competitive advantage and may distinguish entrepreneurial from conservative firms.
Radošević, S., Woodward, R., Yoruk, E.
core