Results 131 to 140 of about 280,047 (395)

A chondroblastic osteosarcoma of the coronoid process mimicking a fragmented coronoid process in a dog [PDF]

, 2016
A 6-year-old Rhodesian Ridgeback was presented with a 1.5 year history of right forelimb lameness. Clinical, radiological and computed tomographic findings suggested the presence of fragmented medial coronoid process.
Cirkel, Koen, De Rycke, Lieve, Gielen, Ingrid, Rasenberg, Wilhelmus Sebastianus Johannes, van Bree, Henri   +4 more
core   +1 more source

Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement

International Forum of Allergy and Rhinology, 2018
Tissue eosinophils are characteristic of inflammation in most but not all patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and may be useful for defining subgroups and making treatment choices.
H. Lou, N. Zhang, C. Bachert, Luo Zhang
semanticscholar   +1 more source

PD‐L1 on Tumor‐Derived Extracellular Vesicles Induces CD8+ T Cell Terminal Exhaustion and Mediates Anti‐PD‐1 Resistance in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
Immunotherapy fails in head and neck squamous cell carcinoma (HNSCC) due to terminally exhausted T (Texterm) cells. Tumor‐derived PD‐L1+ extracellular vesicles promote CD8‐Texterm cells differentiation by upregulating BATF. Stromal Texterm density serves as a potent biomarker for predicting immunotherapy resistance, highlighting a novel EV‐mediated ...
Ruihua Fang, Bixue Huang, Yun Li, Zhimou Cai, Yicheng Deng, Xiaoqing Cen, Wei Sun, Jinhong Zhang, Zhenglin Xu, Wenbin Guo, Yi Lyu, Shiyun Luo, Zhesheng Chen, Kexing Lyu, Weiping Wen, Wenbin Lei   +15 more
wiley   +1 more source

Retrospective Study of Chronic Coughing in Dogs in a Referral Centre in the UK: 329 Cases (2012–2021)

Animals
Chronic coughing is a common complaint in small animal medicine and it has an extensive differential diagnosis with very different treatment and prognosis. Coughing is considered chronic when it lasts at least 8 weeks.
Carla Asorey Blazquez, Ico Jolly Frahija, Arran Smith, Rachel Miller, Mayank Seth, Edgar Garcia Manzanilla, Ferran Valls Sanchez   +6 more
doaj   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

A Review on Cyperus rotundus: Ancient Weed to Modern Elixir of Life Phytochemistry and Therapeutic Uses of Cyperus rotundus (Mustaka)

Pharmaceutical and Biomedical Research, 2021
Background: Since time immemorial, humans have identified several herbs to treat various ailments. With the advancement of science and state-of-the-art technologies, different herbal extracts and chemical constituents of herbs were identified as ...
Hemanth Kumar Kandikattu , Farhath Khanum, Narayanappa Amruta, V.V.P.C. Narayana, Doddaga Srinivasulu   +4 more
doaj  

Somatic Mutations of TSC2 or MTOR Characterize a Morphologically Distinct Subset of Sporadic Renal Cell Carcinoma With Eosinophilic and Vacuolated Cytoplasm

American Journal of Surgical Pathology, 2019
The differential diagnosis of renal cell neoplasms with solid or nested architecture and eosinophilic cytoplasm has become increasingly complex. Despite recent advances in classifying a number of entities exhibiting this morphology, some tumors remain in
Ying-bei Chen, Leili Mirsadraei, G. Jayakumaran, H. Al-Ahmadie, S. Fine, A. Gopalan, S. Sirintrapun, S. Tickoo, V. Reuter   +8 more
semanticscholar   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Diagnosis of pancreatic disease in feline platynosomosis [PDF]

, 2017
Objectives: Platynosomum species are cat-specific parasitic trematodes that parasitize the biliary ducts and gall bladder. Due to the common connection to the major duodenal papilla of the pancreas and common bile ducts in addition to the periductal ...
Illanes, Oscar, Ketzis, Jennifer, Köster, Liza, Rajeev, Sreekumari, Shell, Linda   +4 more
core   +1 more source

Severe Eosinophilic Asthma

Journal of Clinical Medicine, 2019
Asthma is a heterogeneous disease with varying severity. Severe asthma is a subject of constant research because it greatly affects patients’ quality of life, and patients with severe asthma experience symptoms, exacerbations, and medication side effects.
Agamemnon Bakakos, S. Loukides, P. Bakakos   +2 more
semanticscholar   +1 more source