Results 131 to 140 of about 103,530 (323)

The thioredoxin system: Balancing redox responses in immune cells and tumors

open access: yesEuropean Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
The thioredoxin (TRX) system is a critical contributor to cellular redox homeostasis in all living cells. Here, we review the key roles of TRX for activation, proliferation, and responses in T cells, B cells, and myeloid cells. Further, we conceptualize how this knowledge may be therapeutically exploited for cancer treatment.
Jonathan Muri, Manfred Kopf
wiley   +1 more source

Chronic eosinophilic pneumonia: clinical perspectives

open access: yesTherapeutics and Clinical Risk Management, 2019
Matthew Crowe,1 Drew Robinson,2 Malvika Sagar,3 Li Chen,4 Shekhar Ghamande1 1Department of Medicine, Division of Pulmonary and Critical Care, Baylor Scott and White Medical Center, Temple, TX, USA; 2Department of Medicine, Baylor Scott and White Medical
Crowe M   +4 more
doaj  

Assessment of chronic rhinosinusitis with nasal polyps: Development of the Nasal Polyp Patient Assessment Scoring Sheet tool

open access: yesLaryngoscope Investigative Otolaryngology
Background Chronic rhinosinusitis (CRS) is a heterogeneous disorder with a wide range of validated subjective and objective assessment tools to assess disease severity.
Saad Alsaleh   +16 more
doaj   +1 more source

Eosinophilic otitis media a literature review [PDF]

open access: yes, 2013
Eosinophilic otitis media is actually a recent introduction. These patients may manifest with sudden hearing loss. There may be associated bronchial asthma and allergic rhinitis. Diagnostic criteria of this condition are rather vague.
Thiagarajan, Balasubramanian
core   +1 more source

New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma [PDF]

open access: yes, 2017
Introduction: Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-acting beta2-agonist (LABA) are the preferred long-term treatment for adults and adolescents with symptomatic asthma.
Thomson, Neil C.
core   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica   +6 more
wiley   +1 more source

Gastroenterology Practice Patterns Contribute to Missed Diagnoses of Eosinophilic Gastritis and Duodenitis

open access: yesGastro Hep Advances, 2023
Background and Aims: Eosinophilic gastritis and eosinophilic duodenitis (EoG/EoD) are often misdiagnosed as functional gastrointestinal (GI) disorders. Consequently, patients with GI symptoms of EoG/EoD may not undergo the necessary steps for diagnosis ...
Mirna Chehade   +2 more
doaj  

Eosinophilic granulomatosis with polyangiitis (EGPA) and PRES: a case-based review of literature in ANCA-associated vasculitides [PDF]

open access: yes, 2015
Eosinophilic granulomatosis with polyangiitis (EGPA) is a small-sized vessel systemic necrotizing vasculitis and belongs to the family of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides.
Barilaro, Giuseppe   +3 more
core   +1 more source

Metastatic sporadic paraganglioma with EWSR1::CREM gene fusion: A unique molecular profile that expands the phenotypic diversity of the molecular landscape of the EWSR1::CREM gene fusion positive tumors

open access: yesGenes, Chromosomes and Cancer, Volume 62, Issue 2, Page 85-92, February 2023., 2023
Abstract Chromosomal translocations with gene fusions are uniquely rare events in paraganglioma, mostly involving UBTF::MAML3 gene fusion. Precedent literature suggests that tumors involving MAML3 gene fusion correlate with poor clinical outcomes. Herein, we report a case of metastatic sporadic paraganglioma harboring EWSR1::CREM gene fusion in a 36 ...
Sehrish Javaid   +4 more
wiley   +1 more source

A Review on Cyperus rotundus: Ancient Weed to Modern Elixir of Life Phytochemistry and Therapeutic Uses of Cyperus rotundus (Mustaka)

open access: yesPharmaceutical and Biomedical Research, 2021
Background: Since time immemorial, humans have identified several herbs to treat various ailments. With the advancement of science and state-of-the-art technologies, different herbal extracts and chemical constituents of herbs were identified as ...
Hemanth Kumar Kandikattu   +4 more
doaj  

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