Results 141 to 150 of about 280,047 (395)

Intratumoral Fusobacterium nucleatum Drives Cancer‐Associated Fibroblasts Enrichment and Immune Exclusion in Esophageal Squamous Cell Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi, Qingjiang Hu, Kazuki Omachi, Kosuke Kanemitsu, Hajime Otsu, Yusuke Yonemura, Taro Tobo, Yoshifumi Baba, Masaaki Iwatsuki, Koshi Mimori   +9 more
wiley   +1 more source

Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype phenotype correlations [PDF]

, 1996
We have generated a mouse carrying the human G551D mutation in the cystic fibrosis transmembrane conductance regulator gene (CFTR) by a one-step gene targeting procedure.
Alton, Ewfw, Delaney, S. J., Dorin, J. R., Farley, R., Hume, D. A., Lamb, D., Lovelock, P. K., Lunn, D. P., Porteous, D. J., Smith, S. N., Thomson, S. A., Wainwright, B. J.   +11 more
core   +2 more sources

Eosinophilic granulomatosis with polyangiitis: A review.

Autoimmunity Reviews, 2022
White Jpe, S. Dubey
semanticscholar   +1 more source

BiT‐HyMLPKANClassifier: A Hybrid Deep Learning Framework for Human Peripheral Blood Cell Classification Using Big Transfer Models and Kolmogorov–Arnold Networks

Advanced Intelligent Systems, EarlyView.
This study presents BiT‐HyMLPKANClassifier, a novel hybrid deep learning framework for automated human peripheral blood cell classification. Model combines Big Transfer models with multilayer perceptron and efficient Kolmogorov–Arnold Network architectures, achieving over 97% accuracy.
Ömer Miraç KÖKÇAM, Ferhat UÇAR
wiley   +1 more source

A Case Report of Isotretinoin: Acute Eosinophilic Pneumonia, A Rare Adverse Reaction

Indian Journal of Dermatology
This is a case of acute eosinophilic pneumonia (AEP) in a 21-year-old woman with acne vulgaris who was treated with isotretinoin. During treatment, her blood tests showed normal results until the third month, when there was a slight increase in ...
Kadir Küçük
doaj   +1 more source

The effects of anti-sense interleukin-5 gene transferred by recombinant adeno-associated virus in allergic rats [PDF]

, 2008
The accumulation and infiltration of eosinophils in airways is one of the most important characteristics of asthma, and is mediated partly by secretion of IL-5 from Th2 lymphocytes.
Chao Cao, Daxiong Zeng, Qingfeng Song, Weining Xiong, Xiansheng Liu, Yong Cao, Yongjian Xu   +6 more
core   +1 more source

Churg-Strauss Syndrome with Necrosis of Toe Tips [PDF]

, 2011
Churg-Strauss syndrome (CSS) is a granulomatous necrotizing vasculitis of unknown etiology associated with bronchial asthma. Despite affecting small to medium-sized vessels, necrosis of the digits due to vasculitis is extremely rare.
Hasegawa, Kenjiro, Ikeda, Genyo, Kanehiro, Arihiko, Kimata, Yoshihiro, Miyahara, Nobuaki, Nojima, Daisuke, Okada, Chiharu, Tanimoto, Mitsune, Tanimoto, Yasushi, Waseda, Koichi   +9 more
core   +1 more source

Functional luminal imaging probe topography: an improved method for characterizing esophageal distensibility in eosinophilic esophagitis [PDF]

, 2012
Zhiyue Lin, Peter J. Kahrilas, Ying Xiao, Frédéric Nicodème, Nirmala Gonsalves, Ikuo Hirano, John E. Pandolfino   +6 more
openalex   +1 more source

Targeting the Interleukin-5 Pathway for Treatment of Eosinophilic Conditions Other than Asthma

Frontiers in Medicine, 2018
Improved understanding of the contribution of eosinophils to various chronic inflammatory conditions, most notably allergic asthma, has encouraged development of monoclonal antibodies specifically targeting mediators and surface receptors involved in ...
F. Roufosse
semanticscholar   +1 more source

Factor Analysis‐Based Quantitative Endotyping Improves Associations With CRS Cross‐Sectional and Longitudinal Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease characterized by persistent sinonasal inflammation. There is increasing interest in endotype‐based classification, which categorizes CRS based on underlying inflammatory pathways.
Brooke N. Gleason, Zhidi Luo, Aditi Agarwal, Siyuan Dong, Regan L. Harmon, Junqin Bai, Chun‐Kang Liao, Julia Huang, David B. Conley, Kevin C. Welch, Robert C. Kern, Stephanie S. Smith, Anju T. Peters, Whitney S. Stevens, Atsushi Kato, Lutfiyya N. Muhammad, Bruce K. Tan   +16 more
wiley   +1 more source