Results 151 to 160 of about 270,393 (395)
EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy
Advanced Science, EarlyView.This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu +7 more
wiley +1 more source
Feline gastrointestinal eosinophilic sclerosing fibroplasia associated with Candida albicans
Veterinary Medicine and ScienceFeline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF) is a rare and poorly understood disease characterised by the infiltration of eosinophils and the development of fibrous tissue within the gastrointestinal tract of cats.
Angel Almendros +3 more
doaj +1 more source
The Relationship of Hand-Schuller-Christian's Disease, Letterer-Siwe's Disease and Eosinophilic Granulomas of Bone [PDF]
, 1949 Poul Hansen
openalex +1 more source
Advanced Science, EarlyView.This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo +17 more
wiley +1 more source
Advanced Science, EarlyView.During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li +5 more
wiley +1 more source
Advanced Science, EarlyView.IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source
A case of eosinophilic fasciitis and generalized morphea overlap [PDF]
, 2020 A 60-year old man developed skin hardening and edema on his extremities. Although he had been treated with oral prednisolone at another hospital, skin stiffness relapsed during tapering of prednisolone.
Watanabe, Yukina +2 more
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