Results 51 to 60 of about 37,784 (163)

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Cow's milk protein allergy in children: a practical guide

Italian Journal of Pediatrics, 2010
A joint study group on cow's milk allergy was convened by the Emilia-Romagna Working Group for Paediatric Allergy and by the Emilia-Romagna Working Group for Paediatric Gastroenterology to focus best practice for diagnosis, management and follow-up of ...
Calzone Luigi, Baldi Francesco, Bendandi Barbara, Caffarelli Carlo, Marani Miris, Pasquinelli Pamela   +5 more
doaj   +1 more source

Primary cardiac T‐cell rich large B‐cell lymphoma causing aortic stenosis with metastasis in a Warmblood

Equine Veterinary Education, Volume 38, Issue 8, Page e488-e495, August 2026.
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot, F. Z. X. Lean, H. M. Martineau, B. Dunkel, J. Reed   +4 more
wiley   +1 more source

Eosinophilic disorders

, 2007
Eosinophilic inflammatory responses occur in association with multiple disorders. Although the initial cause and the affected organs vary among the different eosinophilic disorders, there are only 2 major pathways that mediate eosinophilia: (1) cytokine ...
Simon, Hans-Uwe, Simon, Dagmar
core   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, Volume 2, Issue 3, July 2026.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Magnetic Resonance Imaging Features of Intravascular Osteosarcoma Affecting the Ventral Internal Vertebral Venous Plexus Causing Cervical Myelopathy in a Dog

Veterinary Radiology &Ultrasound, Volume 67, Issue 4, July 2026.
ABSTRACT A 10.5‐year‐old male castrated Standard Poodle was referred for the evaluation of chronic C6–T2 myelopathy. MRI revealed a severe asymmetric enlargement of the ventral internal vertebral venous plexus, intervertebral/vertebral veins, and possibly the C6 basivertebral vein, with secondary mild spinal cord compression.
Robert Wise, Rachel Durrwachter, Nathan Fanzone, Wilfried Mai   +3 more
wiley   +1 more source

A Bi-Institutional Study of Gastrointestinal and Hepatic Manifestations in Children With PTEN Hamartoma Tumor Syndrome

Gastro Hep Advances
Background and Aims: PTEN hamartoma tumor syndrome (PHTS) confers a high risk of specific cancers and is the most common genetic cause of autism spectrum disorder (ASD). Gastrointestinal (GI) phenotypes in PHTS are poorly characterized in children. Thus,
Darren Liu, Suzanne P. MacFarland, Lamis Yehia, Melani M. Duvall, Petar Mamula, Jacob A. Kurowski, Colleen S. Greene, Kadakkal Radhakrishnan, Charis Eng   +8 more
doaj   +1 more source

Current Trends in Tolerance Induction in Cow's Milk Allergy: From Passive to Proactive Strategies

Frontiers in Pediatrics, 2019
This review addresses the current strategies of inducing tolerance development in infant and childhood cow's milk protein allergy (CMPA). The change in prevention strategies for CMPA has been emphasized based on the lack of evidence to support the ...
Cansin Sackesen, Derya Ufuk Altintas, Aysen Bingol, Gulbin Bingol, Betul Buyuktiryaki, Esen Demir, Aydan Kansu, Zarife Kuloglu, Zeynep Tamay, Bulent Enis Sekerel   +9 more
doaj   +1 more source

Extranodal natural killer/T‐cell lymphoma: From fatal to curable

CA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.
Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is one of the most aggressive non‐Hodgkin lymphomas characterized by NK‐cell or T‐cell origins, a geographic prevalence in Asian and South American populations, and Epstein–Barr virus (EBV) infection.
Jie Xiong, Yok‐Lam Kwong, Laurence de Leval, Shu‐Nan Qi, Choon Kiat Ong, Philippe Gaulard, Arnaud Jaccard, Steven M. Horwitz, Ye‐Xiong Li, Sai‐Juan Chen, Ritsuro Suzuki, Won Seog Kim, Wei‐Li Zhao   +12 more
wiley   +1 more source

Eosinophilic otitis media a literature review [PDF]

, 2013
Eosinophilic otitis media is actually a recent introduction. These patients may manifest with sudden hearing loss. There may be associated bronchial asthma and allergic rhinitis. Diagnostic criteria of this condition are rather vague.
Thiagarajan, Balasubramanian; Stanley Medical College
core