Results 201 to 210 of about 23,885 (300)

IFNγ Signaling Impairs Regulatory B Cell Function Resulting in Worse Control of Esophageal Food Allergy

open access: yesAllergy, Volume 80, Issue 10, Page 2824-2836, October 2025.
We used patient samples and a murine model to understand the contribution of Bregs to EoE immunopathology. We find that Breg‐derived IL‐10 is important for controlling EoE, but that Breg expansion and function are impaired in this condition. We identify IFNγ as a key negative regulator of Breg function in mice and patients with EoE. Bregs, regulatory B
Rachel L. Clement   +4 more
wiley   +1 more source

Validation of the novel Eosinophilic Esophagitis Symptom Questionnaire. [PDF]

open access: yesJ Allergy Clin Immunol Glob
McCann E   +6 more
europepmc   +1 more source

ORAL PREDNISONE (P) IS NOT SUPERIOR TO TOPICAL FLUTICASONE (F) IN THE TREATMENT OF ALLERGIC EOSINOPHILIC ESOPHAGITIS (AEE)

open access: bronze, 2006
Elizabeth Schaefer   +8 more
openalex   +1 more source

Eosinophilic Esophagitis After Radiofrequency Ablation of Barrett's Esophagus in a 41-Year-Old Man. [PDF]

open access: yesAm J Case Rep
Mokrowiecka A   +5 more
europepmc   +1 more source

Combined Lyon and Milan Scores Predict Gerd Management Outcome Better Than Either Score Alone or Their Individual Components

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 7, Page 710-721, October 2025.
The Lyon and Milan scores outperformed AET and DeMeester score in predicting outcomes in GERD patients. When concordant, they provide optimal predictive accuracy, guiding escalation of therapy. ABSTRACT Background Confidence in gastro‐oesophageal reflux disease (GERD) diagnosis is crucial to improve outcomes from escalation of treatment. The Lyon score
Stefano Siboni   +27 more
wiley   +1 more source

Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk

open access: yesBritish Journal of Haematology, Volume 207, Issue 4, Page 1565-1577, October 2025.
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez   +34 more
wiley   +1 more source

Disrupted mucosal vascular barrier in eosinophilic esophagitis. [PDF]

open access: yesSci Rep
Lenti MV   +17 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy