Results 291 to 300 of about 110,204 (324)

Characterization of Eosinophilic Esophagitis From the European Pediatric Eosinophilic Esophagitis Registry (pEEr) of ESPGHAN

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2022
Objectives: Few pediatric data on phenotypic aspects of eosinophilic esophagitis (EoE) are available. The pEEr registry was developed to prospectively characterize children with EoE from Europe and Israel. Methods: pEEr is an ongoing prospective registry
S. Oliva, J. Dias, F. Rea, M. Malamisura, M. C. Espinheira, Alexandra Papadopoulou, Eleni Koutri, D. Rossetti, R. Orel, M. Homan, O. Bauraind, M. Auth, C. G. Junquera, S. Velde, M. Kori, K. Huysentruyt, V. Urbonas, E. Roma, S. Fernández, G. Domínguez-Ortega, E. Zifman, Panayota Kafritsa, E. Miele, N. Zevit   +23 more
semanticscholar   +1 more source

Diagnosis and management of eosinophilic esophagitis in children: An update from the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN).

Journal of Pediatric Gastroenterology and Nutrition - JPGN
INTRODUCTION Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus characterized by symptoms of esophageal dysfunction and histologically by predominantly eosinophilic infiltration of the squamous epithelium.
J. Amil-Dias, Salvatore Oliva, A. Papadopoulou, Mike Thomson, C. Gutiérrez‐Junquera, Nicolas Kalach, R. Orel, M. Auth, Danielle Nijenhuis‐Hendriks, C. Strisciuglio, Olivia Bauraind, Sonny Chong, Gloria Dominguez Ortega, Sonia Férnandez Férnandez, Mark Furman, Roger García-Puig, F. Gottrand, M. Homan, K. Huysentruyt, Aco Kostovski, S. Otte, F. Rea, Eleftheria Roma, Claudio Romano, C. Tzivinikos, V. Urbonas, S. Velde, T. Zangen, N. Zevit   +28 more
semanticscholar   +1 more source

S659 Prevalence and Costs of Eosinophilic Esophagitis in the United States

Clinical Gastroenterology and Hepatology
BACKGROUND AND AIMS Eosinophilic esophagitis (EoE) has been continually increasing in prevalence but current estimates are lacking. We aimed to determine updated estimates of the prevalence and medical costs associated with EoE in the United States ...
Hannah L. Thel, Chelsea Anderson, Angela Z. Xue, Elizabeth T. Jensen, E. Dellon   +4 more
semanticscholar   +1 more source

Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis.

New England Journal of Medicine
BACKGROUND Benralizumab is an eosinophil-depleting anti-interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.
M. Rothenberg, Evan S. Dellon, M. H. Collins, A. Bredenoord, I. Hirano, Kathryn A Peterson, L. Brooks, J. Caldwell, Harald Fjällbrant, H. Grindebacke, C. Ho, Matthew Keith, C. Mccrae, Dominic Sinibaldi, Wendy I White, Catherine J Datto   +15 more
semanticscholar   +1 more source

Dupilumab for Eosinophilic Esophagitis in Patients 1 to 11 Years of Age.

New England Journal of Medicine
BACKGROUND Dupilumab is a human monoclonal antibody that blocks interleukin-4 and interleukin-13 pathways and has shown efficacy in five different atopic diseases marked by type 2 inflammation, including eosinophilic esophagitis in adults and adolescents.
M. Chehade, Evan S. Dellon, J. Spergel, M. H. Collins, M. Rothenberg, R. Pesek, I. Hirano, Ruiqi Liu, E. Laws, E. Mortensen, R. Martincova, A. Shabbir, E. Mccann, Mohamed A Kamal, M. Kosloski, J. Hamilton, C. Samuely, Wei Keat Lim, M. Wipperman, Annamaria Farrell, Naimish Patel, G. Yancopoulos, L. Glotfelty, J. Maloney   +23 more
semanticscholar   +1 more source

Current treatment options and long-term outcomes in patients with eosinophilic esophagitis

Expert Review of Clinical Immunology, 2022
Introduction Dietary and pharmacological (proton pump inhibitors, swallowed topical corticosteroids) therapies are effective for induction of clinical and histological remission of eosinophilic esophagitis.
A. Lucendo, J. Molina-Infante
semanticscholar   +1 more source

Eosinophilic Esophagitis

Immunology and Allergy Clinics of North America, 2015
Eosinophilic esophagitis (EoE) is a clinicopathologic disease of increasing prevalence. Because EoE is a chronic disease, its prevalence will continue to increase. Antigen triggers, including food and aeroallergens, drive eosinophilic and T helper cell type 2 inflammation, resulting in subepithelial fibrosis; this esophageal remodeling is the likely ...
openaire   +4 more sources

Global Incidence and Prevalence of Eosinophilic Esophagitis, 1976-2022: A Systematic Review and Meta-Analysis.

Clinical Gastroenterology and Hepatology, 2023
Jong Woo Hahn, Kwan-Hang Lee, J. Shin, Seong Ho Cho, S. Turner, Jung U Shin, A. Yeniova, A. Koyanagi, L. Jacob, Lee Smith, G. Fond, L. Boyer, S. Lee, R. Kwon, Soeun Kim, Y. Shin, S. Rhee, J. Moon, J. Ko, D. Yon, N. Papadopoulos   +20 more
semanticscholar   +1 more source

Eosinophilic Esophagitis

Gastroenterology Clinics of North America, 2008
Eosinophilic esophagitis (EoE) is a disease based on a clinicopathologic diagnosis that involves a localized eosinophilic inflammation of the esophagus. A significant increase in the diagnosis of pediatric EoE has occurred over the past 10 years not only due to a greater recognition of the disease among gastroenterologists, allergists, and pathologists
openaire   +2 more sources

Esophageal dilation in eosinophilic esophagitis

Best Practice & Research Clinical Gastroenterology, 2015
Tissue remodeling with scaring is common in adult EoE patients with long standing disease. This is the major factor contributing to their complaints of solid food dysphagia and recurrent food impactions. The best tests to define the degree of remodeling are barium esophagram, high resolution manometry and endoscopy.
openaire   +2 more sources